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NIH T32 Training Grant in Joint Health

The NIH T32 Training Grant in Joint Health supports post-doctoral fellowships and short-term medical student research. The grant is directed by Rick Sumner, PhD and co-directed by Markus Wimmer, PhD and Anne-Marie Malfait, MD, PhD.

 

Overview

Three people walking down a corridor

This multi-disciplinary post-doctoral training program in musculoskeletal biology emphasizes research training in joint health, encompassing three major programmatic areas: osteoarthritis, total joint replacement and small molecule therapeutics.  Training will take place in the laboratories of NIH funded faculty in two basic science departments (Anatomy & Cell Biology and Physiology & Biophysics) and three clinical departments (Internal Medicine, Orthopedic Surgery and Pediatrics). The preceptors are internationally respected scientists and physician-scientists devoted to musculoskeletal research, with a special focus on osteoarthritis (including pain), cartilage and bone biology, total joint replacement, and muscle physiology. We encourage candidates with a medical degree to apply in addition to those with PhD’s. After completing our program, the trainees will be better able to become independent, team-oriented, principal investigators. The program also supports 3-month “short-term” slots for medical students. Trainees have many resources available including the T32/P30 Joint Seminar Series, which features internationally renowned scholars.

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Personal statements from trainees
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Mentor (PI) Research area
Buchman, Aron, MD
(Lab)
Aging, motor system, frailty, risk factors, dementia
Chubinskaya, Susan, PhD
(Lab)
Osteoarthritis, cartilage trauma, human donor tissue
Fill, Michael, PhD
(Lab)
Small molecule therapeutics, Intracellular Ca, muscle, ryanodine receptor, inositol trisphosphate receptor
Gupta, Vineet, PhD
(Lab)
Small molecule therapeutics, inflammation, autoimmune diseases, CD11b/CD18 agonists, lupus
Hallab, Nadim James, PhD Total joint replacement, Implant degradation, biological reactivity to implant debris, inflammasome, immunity, metal sensitivity
Jacobs, Joshua, MD
(Lab)
Total joint replacement, retrieval analysis, biocompatibility, corrosion and wear
Ko, Frank, PhD (Lab) Musculoskeletal homeostasis, disease, and repair
Lundberg, Hannah, PhD
(Lab)
Total joint replacement, computational biomechanics, finite element analysis
Maki, Carl, PhD
(Lab)
Small molecule therapeutics, cancer cell biology, p53, therapy resistance, osteosarcoma
Malfait, Anne-Marie, MD, PhD
(Lab)
Osteoarthritis, pain, heritable connective tissue diseases
Miller, Rachel, PhD
(Lab)
Osteoarthritis, mechanical forces, pain, joint damage
Plaas, Anna, PhD
(Lab)
Osteoarthritis, hyaluronan metabolism, inflammation, tendinopathy, regeneration
Pourzal, Robin, PhD
(Lab)
Total joint replacement, failure analysis, retrieval studies, adverse local tissue reaction
Pratap, Jitesh, PhD
(Lab)
Regulatory mechanisms of bone metastasis
Ramos-Franco, Josefina, MD, PhD
(Lab)
Small molecule therapeutics, intracellular Ca signaling, chondrocytes, osteocytes, inositol trisphosphate receptor, OA pain
Rios, Eduardo, Lic
(Lab)
Small molecule therapeutics, calcium signaling, skeletal muscle
Ross, Ryan, PhD
(Lab)
Mineralization and mineral metabolism, the hormonal role of bone, skeletal effects of HIV and antiretrovirals, circulating biomarkers
Shafikhani, Sasha, PhD
(Lab)
Small molecule therapeutics, wound healing, immune dysregulation, articular cartilage
Spagnoli, Anna, MD Fracture repair, joint development, osteogenesis, chondrogenesis, osteoarthritis
Sumner, D. Rick, PhD
(Lab)
Total joint replacement, bone regeneration, bone quality, peri-implant osteolysis, biomarkers, osteoarthritis
Wimmer, Markus, PhD
(Lab)
Total joint replacement, tribology, motion analysis, joint biomechanics, articular cartilage mechanobiology

 

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