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NIH T32 Training Grant in Joint Health

The NIH T32 Training Grant in Joint Health supports post-doctoral fellowships and short-term medical student research. The grant is directed by Rick Sumner, PhD and co-directed by Markus Wimmer, PhD and Anne-Marie Malfait, MD, PhD.



Three people walking down a corridor

This multi-disciplinary post-doctoral training program in musculoskeletal biology emphasizes research training in joint health, encompassing three major programmatic areas: osteoarthritis, total joint replacement and small molecule therapeutics.  Training will take place in the laboratories of NIH funded faculty in two basic science departments (Anatomy & Cell Biology and Physiology & Biophysics) and three clinical departments (Internal Medicine, Orthopedic Surgery and Pediatrics). The preceptors are internationally respected scientists and physician-scientists devoted to musculoskeletal research, with a special focus on osteoarthritis (including pain), cartilage and bone biology, total joint replacement, and muscle physiology. We encourage candidates with a medical degree to apply in addition to those with PhD’s. After completing our program, the trainees will be better able to become independent, team-oriented, principal investigators. The program also supports 3-month “short-term” slots for medical students. Trainees have many resources available including the T32/P30 Joint Seminar Series, which features internationally renowned scholars.

Personal statements from trainees
Mentor (PI) Research area
Buchman, Aron, MD
Aging, motor system, frailty, risk factors, dementia
Chubinskaya, Susan, PhD
Osteoarthritis, cartilage trauma, human donor tissue
Fill, Michael, PhD
Small molecule therapeutics, Intracellular Ca, muscle, ryanodine receptor, inositol trisphosphate receptor
Gupta, Vineet, PhD
Small molecule therapeutics, inflammation, autoimmune diseases, CD11b/CD18 agonists, lupus
Hallab, Nadim James, PhD Total joint replacement, Implant degradation, biological reactivity to implant debris, inflammasome, immunity, metal sensitivity
Jacobs, Joshua, MD
Total joint replacement, retrieval analysis, biocompatibility, corrosion and wear
Ko, Frank, PhD (Lab) Musculoskeletal homeostasis, disease, and repair
Lundberg, Hannah, PhD
Total joint replacement, computational biomechanics, finite element analysis
Maki, Carl, PhD
Small molecule therapeutics, cancer cell biology, p53, therapy resistance, osteosarcoma
Malfait, Anne-Marie, MD, PhD
Osteoarthritis, pain, heritable connective tissue diseases
Miller, Rachel, PhD
Osteoarthritis, mechanical forces, pain, joint damage
Plaas, Anna, PhD
Osteoarthritis, hyaluronan metabolism, inflammation, tendinopathy, regeneration
Pourzal, Robin, PhD
Total joint replacement, failure analysis, retrieval studies, adverse local tissue reaction
Pratap, Jitesh, PhD
Regulatory mechanisms of bone metastasis
Ramos-Franco, Josefina, MD, PhD
Small molecule therapeutics, intracellular Ca signaling, chondrocytes, osteocytes, inositol trisphosphate receptor, OA pain
Rios, Eduardo, Lic
Small molecule therapeutics, calcium signaling, skeletal muscle
Ross, Ryan, PhD
Mineralization and mineral metabolism, the hormonal role of bone, skeletal effects of HIV and antiretrovirals, circulating biomarkers
Shafikhani, Sasha, PhD
Small molecule therapeutics, wound healing, immune dysregulation, articular cartilage
Spagnoli, Anna, MD Fracture repair, joint development, osteogenesis, chondrogenesis, osteoarthritis
Sumner, D. Rick, PhD
Total joint replacement, bone regeneration, bone quality, peri-implant osteolysis, biomarkers, osteoarthritis
Wimmer, Markus, PhD
Total joint replacement, tribology, motion analysis, joint biomechanics, articular cartilage mechanobiology


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