PhD, Ghent University, Ghent, Belgium
MD, Ghent University, Ghent, Belgium
BS, Ghent University, Ghent, Belgium
Pain in osteoarthritis is the focus of my research group at Rush University. I have 24 years of expertise with animal models of rheumatoid arthritis and osteoarthritis. During my 8-year tenure as Senior Principal Investigator at Pfizer, I was project leader in the Research Team for development of disease-modifying osteoarthritis drugs (DMOADs). In this capacity, I was directly involved with all aspects of the DMOAD discovery process, including target identification, compound development, proof-of-concept studies, animal modeling, safety assessments, biomarker development and design of phase I clinical trials. Rush provides a unique environment for the study of musculoskeletal diseases and allows me to integrate my early research training (which focused on the areas of cartilage biology and proteases, animal models of arthritis and cytokine regulation), my prior exposure to clinical rheumatology, and my pharmaceutical experience, in order to establish a laboratory for translational osteoarthritis research.
For more information, please see the [lab website].
Please see [Pubmed]