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Ryan Ross, PhD

Ryan Ross, PhD
Associate Professor
Department of Anatomy & Cell Biology, RUSH Medical College
Associate Professor, Department of Microbial Pathogens and Immunity
Associate Professor, Department of Orthopedic Surgery
Education

PhD, University of Notre Dame

Research Areas

Skeletal mineralization, effects of HIV and antiretrovirals on bone, the hormonal role of the skeleton

Contact Info:

1750 W. Harrison St.
Suite 1413A
Chicago, IL 60612
Phone: (312) 563-3859
Fax: (312) 942-5744
ryan_ross@rush.edu
Links:
Biography

Ryan Ross, PhD, is an associate professor in the Department of Anatomy & Cell Biology with conjoint appointments in the Departments of Microbial Pathogens and Immunity and Orthopedic Surgery. He received his BS in Chemical Engineering from the University of California at Riverside and his PhD in Bioengineering from the University of Notre Dame. He conducted his postdoctoral training at Rush University Medical Center in bone biology. His research focuses on the skeleton with an emphasis on bone quality and the potential hormonal role of bone. Ongoing projects within the lab include (1) investigating the regulation of fibroblast growth factor 23 (FGF23) by sclerostin and the potential for manipulation of Wnt signaling to improve X-linked hypophosphatemia (XLH), (2) disentangling the relative contributions of HIV and antiretroviral therapies to bone loss in people living with HIV, (3) assessing the effects of bone-fat organ crosstalk on anthropometric changes in people living with HIV initiating and switching antiretroviral therapies, and (4) determining the link between age-related bone loss and cognitive decline.

Publications

Complete list of published work on PubMed

Complete list of published work on Scopus

Grants

Current

NIH/NIAMS R01AR081151: “Bone and Fat Cross-talk in Antiretroviral Therapy (ART) Treated HIV Patients” Principal Investigator: Ryan Ross

NIH/NIAMS K01AR073923: “Sclerostin Regulation of Skeletal Mineralization and Phosphate Metabolism”  Principal Investigator: Ryan Ross

NIH/NIDCR R03DE029873: “Assessing the function role of sclerostin in periodontal disease in XLH” Principal Investigator: Ryan Ross

NIH/NIAMS R21AR079309: “Characterization of a humanized mouse model to study HIV and ARV effects on bone” Principal Investigator: Ryan Ross

Women’s Interagency HIV Study (WIHS) Subcontract: “The Role of Bone-Derived Hormones in HIV-induced Aging Pathologies”  Subcontract PI: Ryan Ross

 

Past

Rush University Searle Innovators Award: “Patient Intrinsic Factors Predict Peri-implant Osteolysis”  Principal Investigator: Ryan Ross

Orthopaedic Research and Education Foundation (OREF): “Improved Predictions of Orthopaedic Implant Fixation”  Principal Investigator: Ryan Ross

NIH/NIA P30AG010161-PILOT: “Bone Mineral Density as a Risk Factor for Incident Disability”  Lead Principal Investigator: David Bennett, Pilot project PI: Ryan Ross

“Measuring Circulating Biomarkers to Diagnosis Osteolysis Prior to Radiographic Loosening” Orthopaedic Research Society / Orthopaedic Research and Educational Foundation Postdoctoral Fellowship. Role: Principal Investigator July 2015 to July 2016

“Bone Matrix Maturation in a Rat Model of Intra-Cortical Bone Remodeling” NIHR21AR065604 Role: Co-investigator (PI: Sumner) July 2015 to June 2017

“Bone Mineralization Pilot Project” Rush Translational Science Center
Role: Co-investigator (PI: Sumner) September 2013 to August 2015

“Association Between Bone Turnover Markers and Level of Cognition in Older Community Dwelling Individual with Memory Concerns” NIA P30AG010161, David Bennett (PI) Role: Co-investigator (PI: Sumner) July 2014 to June 2015