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Ophthalmology Research

Departmental Research
Departmental Research
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Opthalmology research

The Department of Ophthalmology is deeply committed to the advance of ophthalmic knowledge and the development of new techniques and treatments for the management of ophthalmic disease. Our research efforts are focused in the following three major areas:

  • The study of new therapeutics addressing key causes of vision loss including age-related macular degeneration, diabetic retinopathy, ocular inflammation (uveitis), vitreomacular traction, retinopathy of prematurity, keratoconus, and the ocular complications of AIDS
  • The development and evaluation of new surgical approaches and devices for age-related macular degeneration including implantable drug reservoirs, stem cell implantation and the implantable miniature telescope
  • The testing of new ocular imaging technologies including wide-field Optos angiography and optical coherence tomographic angiography (OCT-A). Grant-funded by the Juvenile Diabetics Research Foundation, we employed the first OCT in Illinois

Our studies

 

Diabetic Retinopathy

  • Protocol AP-comboPDR: a randomized clinical trial evaluating combination therapy with Faricimab + PRP versus vitrectomy + endolaser for the treatment of proliferative diabetic retinopathy (Protocol AP)
    • Primary Investigator (PI): Sara Fard, MD
  • A Randomized Clinical Trial Evaluating Fenofibrate for Prevention of Diabetic Retinopathy Worsening (Protocol AF)
    • Primary Investigator (PI): Mathew MacCumber, MD, PhD
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Diabetic Retinopathy New Image Resized

 


Epiretinal Membranes

  • Randomized Trial Comparing Immediate versus Deferred Surgery for Symptomatic Epiretinal Membranes (Protocol AM)
    • Primary Investigator (PI): Mathew MacCumber, MD, PhD

Neurotrophic Keratitis

  • A Phase 1/2, Multicenter, Double-Masked, Placebo-Controlled Study of KB801 in Subjects with Stage 2 or 3 Neurotrophic Keratitis
    • Primary Investigator (PI): Jonathan Rubenstein, MD

Uveitis

  • Monitoring and Predicting Outcomes of Birdshot Chorioretinopathy: A Clinicogenomics Study
    • Primary Investigator (PI): Veena Raiji, MD

Genetics in Retinal Diseases

  • Secondary study utilizing data collected from participants enrolled in the DRCR Retina Network study (Protocol AF, AM and AP)
    • Primary Investigator (PI): Mathew MacCumber, MD, PhD

Contact us

If you are interested in participating in this research study or would like more information, please contact:

Luma Halig, OD, MS
📧 Eye_Research_Services@rush.edu
📞 (312) 563-5537

When contacting us, please include your first and last name, phone number, email address, and the study you are interested in.