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Cardiopulmonary Sciences: Respiratory Care Research

The goal of the Department of Cardiopulmonary Sciences, Division of Respiratory Care, is to publish original research that impacts cardiopulmonary health care nationally, internationally and at Rush. The division of research includes four areas of focus: bench, simulation, clinical and disease management. Our bench and simulation projects translate either to clinical research or to the improvement of clinical services provided in the medical center.

More specifically, bench research includes aerosol projects and device trials. Simulation research ranges from improving staff clinical skills to introducing new scoring tools and clinical protocols. Clinical research projects include quality improvement, medical devices and observational or randomized clinical trials.

Our work

Bench: Aerosol projects

Anderson AC, Dubosky MN, Bianchi KA, Lopez V, Kaplan CA, Vines DL. Effect of Nebulizer Position on Aerosolized Epoprostenol Delivery in an Adult Lung Model. Respiratory Care. 2015;60(10):OF10.

Bensaleem M, Dubosky M, Anderson A, Vines DL, Fink J. Nebulizer Location and Air trapping Effects on Aerosol Delivery During Airway Pressure Release Ventilation (APRV) in Adult Lung Model. Respiratory Care. 2015;60(10):OF10.

Vines DL, Dubosky MN, Brahmbhatt H. Comparison of Aerosol Drug Deposition Between Aerosol Masks and Mouthpiece Using a Vibrating Mesh Nebulizer in a Spontaneously Breathing Lung Model. Respiratory Care. 2014;59(10):OF29.

Dubosky MN, Vines DL. An Evaluation of Aerosol Output: The Aeroneb Solo Vibrating-Mesh Nebulizer. American Journal of Respiratory and Critical Care Medicine. 2015:A4282, 10.1164

Brahmbhatt H, Dubosky MN, Vines DL. Aerosol Masks Versus Mouthpiece: The Influence of Aerosol Interfaces on Drug Deposition in a Spontaneously Breathing Model. Respiratory Care. 2014;59(10):OF30.

Bench: Device trials

Alodaini S, Dubosky MN, Vines DL. Evaluating The Performance Of Simple Face Mask And Oxy Multi-Mask In Preventing Carbon Dioxide Rebreathing. American Journal of Respiratory and Critical Care Medicine. 2014: A1615, 10.1164.

Scott JB, Dubosky MN, Vines DL. Comparison Of A Nonrebreathing Mask And OxyMulti Mask Prototype: An Analysis Of Oxygen Concentrations Measured In The Trachea Using A High-Fidelity Simulator. American Journal of Respiratory and Critical Care Medicine. 2014: A1623, 10.1164.

Vines DL, Alfozan BA. The Effect Of Adjusting Percent Support On Tidal Volume, Peak Inspiratory Pressure, And Total Inspiratory Work Of Breathing During Proportional Assist Ventilation In A Lung Model. Am J Respir Crit Care Med 189;2014: A4576

Vines D, Dapkus J, Podgorak, T. The role of leak in the synchronization of noninvasive ventilation in a spontaneous breathing infant lung model. 2013. pp. 1-328, #460. (Critical Care Med; 40;12).


Weiss TT, Scott JB, Reed JL, Dubosky MN, Vines DL. Low- Versus High-Fidelity Simulation Training In Laryngeal Mask Airway Placement and Endotracheal Intubation. Respiratory Care. 2015;60(10):OF68.

Reed J, Weiss T, Scott JB, Dubosky MN, Vines DL. Comparison of High-Fidelity Versus Low-Fidelity Simulation When Performing Bag Mask Ventilation. Respiratory Care. 2015;60(10):OF36.

Alijoaid A, Scott JB, Mirza SH, Dubosky MN, Vines DL. Evaluation of a Training Method to Improve Knowledge, Skills and Increase the Clinical Use of Prone Positioning. Respiratory Care. 2014;59(10):OF76.


Dubosky MN, Henriksen M, Vines, DL. Vibrating Mesh Nebulizer Compared to Metered Dose Inhaler in Mechanical Ventilated Patients: A Retrospective Study on Outcomes. Respiratory Care. 2015;60(10):OF9.

Stanley J, Dubosky MN, Vines DL, Yoder M. Correlation between Preoperative and Postoperative Risk Assessment Tolls and Postoperative Pulmonary Complications. American Journal of Respiratory and Critical Care Medicine. 2015:A1092, 10.1164

Vines DL, Meksraiyte E, Scott JB, Dubosky MN, Kakkanad T, Shay E, Gurka D. Higher Respiratory Assesment and Allocation of Therapy (RAAT) Scores May Be Associated with Pulmonary Infections, Atelectasis, and Need for Positive Pressure Ventilation. American Journal of Respiratory and Critical Care Medicine. 2015: A4541,10.1164

Disease management

Alsomali H, Vines DL, Stein BD, Becker EA. Evaluating the Health Literacy and Effectiveness of Written Dry Powder Inhaler Instructions in Patients Diagnosed with Chronic Obstructive Pulmonary Disease. Respiratory Care. 2015;60(10):OF38.

Arroyo J &Becker EA. A needs assessment for the delivery of asthma education to parents of young children. Respiratory Care Education Annual 2014;23:34-44.

Patel AB, Vines DL, Stein BM, & Becker EA. Efficacy of dry powder inhaler patient educational handouts to correcting device use in chronic obstructive pulmonary disease patients and patient ability to generate adequate inspiratory flow rates. Respiratory Care Education Annual 2014; 23:20-30.

Cameron JR, Belice PJ, Becker EA, Balluff Z, McClenton R. A retrospective chart review of asthma guideline adherence within a medical home network in a pediatric population. Journal of Respiratory and Critical Care Medicine. 2015: A1712, 10.1164

Our team