Neurosurgery Research

The Department of Neurological Surgery is deeply committed to advancing knowledge and the pursuit of progress in new techniques and treatments in neurosurgery. As both clinicians and researchers in a dynamic academic medical center, neurosurgeons at Rush consistently translate significant scientific innovations into health gains for patients. Continuous investment in basic biomedical and behavioral discovery in concert with translational science ensures that both of these disciplines remain powerful engines of creativity.

Our research efforts have been focused in the following three broad areas:

Brain tumor and functional neurosurgery

Implantable neurostimulator for the treatment of Parkinson’s disease (INTREPID trial).

Treatment of Parkinson’s Patients Using Levodopa Study
Safety and efficacy study of SYN115 in Parkinson’s patients using levodopa to treat end of dose wearing off (TOZPD).


A concurrently controlled study of LimiFlex™ Paraspinous Tension Band in the treatment of lumbar degenerative spondylolisthesis with spinal stenosis. 

Confirmatory clinical study to support the effectiveness and safety of oxiplex for the reduction of pain and symptoms following lumbar surgery.

An assessment of P-15L bone graft in transforaminal lumbar interbody fusion with instrumentation. 

Endovascular Neurosurgery

Enrich Trial
A multi-center, randomized, clinical trial comparing standard medical management to early surgical hematoma evacuation using minimally invasive parafascicular surgery (MIPS) in the treatment of intracerebral hemorrhage (ICH).

Phil Trial
Study of Phill® Embolic System in the treatment of intracranial dural arteriovenous fistulas.