PhD, Rush Medical College
MS, University of Illinois Medical Center
BS, University of Charleston
Ion channels, bacterial porins, lipid bilayers, patch-clamp techniques, perfusing patch pipettes, silicon-based ion channel sensor, channels of internal membranes in sarcoplasmic reticulum and mitochondria, pressure sensitive channels
The research interests of John M. Tang, PhD are in the areas of ion channels, bacterial porins, lipid bilayers, patch-clamp techniques, perfusing patch pipettes, silicon-based ion channel sensor, channels of internal membranes in sarcoplasmic reticulum and mitochondria, and pressure sensitive channels. Dr. Tang is the web editor of Rush Medical College, Office of Basic Biological Sciences (OBBS) Departments.
Rush Medical College, Office of Basic Biological Sciences (OBBS) Departments:
Department of Anatomy & Cell Biology
Department of Microbial Pathogens and Immunity
Department of Physiology & Biophysics
Anatomy & Cell Biology Research
Microbial Pathogens and Immunity Research
Physiology & Biophysics Research
Outstanding graduate student award. Rush University, Chicago, IL. (1992)
National Institutes of Health traineeship (1985-1989)
Teaching assistantship with full tuition waiver. University of Illinois at the Medical Center, Chicago, IL. (1973-1977)
Dean’s List. University of Charleston, Charleston, W. Va. (1970-1973)
Full tuition scholarship. University of Charleston, Charleston, W. Va. (1970-1973)
Complete list of published work on PubMed
Complete list of published work on Scopus
Complete list of published work on ORCID
Select Publications:
Giri, Janhavi, Tang, John M., Wirth, Christophe, Peneff, Caroline M. and Eisenberg, Bob (2012) “Single Channel Measurements of N-Acetylneuraminic Acid-Inducible Outer Membrane Channel in Escherichia coli.“ European Biophysics Journal 41: 259-271. PMID: 22246445. PMCID: PMC3288477.
Ervin, Eric N., White, Ryan J., Owens, Treggon G., Tang, J. M., and White, Henry S. (2007) “AC Conductance of Transmembrane Protein Channels. The Number of Ionized Residue Mobile Counter-ions at Infinite Dilution.“ Journal of Physical Chemistry 111: 9165-9171. PMID: 17602583.
Wilk, S.J., Petrossian, L., Goryll M., Thornton, T.J., Goodnick, S.M., Tang, J.M., Eisenberg R.S. (2007) “Integrated Electrodes on a Silicon Based Ion Channel Measurement Platform.” Biosensors and Bioelectronics 23: 183-190. PMID: 17507211.
White, Ryan J., Zhang, Bo, Daniel, Susan, Tang, J. M., Ervin, Eric N., Cremer, Paul S. and White, Henry S. (2006) “The Ionic Conductivity of the Aqueous Layer Separating a Lipid Bilayer Membrane and a Glass Support.“ Langmuir 22:10777-10783. PMID: 17129059.
Wilk, S. J., Petrossian, L., Goryll, M., Thornton, T. J., Goodnick, S. M., Tang, J. M., Eisenberg, R. S. and Saraniti, M. (2005) “Ion Channels on Silicon.“ e-Journal of Surface Science and Nanotechnology. 3: p. 184-189.
Wilk, S. J., Petrossian, L., Goryll, M., Tang, J. M., Eisenberg, R. S., Saraniti, M., Goodnick, S. M. and Thornton, T. J. (2005) “Silicon-Based Ion Channel Platforms.” in HCIS-14. p. 201, 2005. Chicago, IL: Springer Proceedings in Physics Series.
Wilk, S. J., Goryll, M., Laws, G. M., Thornton, T. J., Goodnick, S. M., Saraniti, M., Tang, J. M. and Eisenberg, R. S. (2004) “Teflon-coated silicon apertures for supported lipid bilayer membranes.“ Applied Physics Letters 85(15):3307-3309. DOI: 10.1063/1.1805712.
Miedema, H., Meter-Arkema, A., Wierenga, J., Tang J. M., Eisenberg, R. S., Nonner, W., Hektor, H., Gillespie, D. and Meijberg, W. (2004) “Permeation properties of an engineered bacterial OmpF porin containing the EEEE-locus of Ca2+ channels,“ Biophysical Journal 87:3137-3147. PMID: 15326033. PMCID: PMC1304784.
Goryll, M., Wilk, S. J., Laws, G. M., Goodnick S. M., Thornton T. J., Saraniti, M., Tang, J. M. and Eisenberg, R. S. (2004) “Ion Channel Sensor on a Silicon Support.“ Mater. Res. Soc. Symp. Proc. Vol. 820, O7.2.1-6 (2004). Proceedings Title: Nanoengineered Assemblies and Advanced Micro/Nanosystems Editors (Symposium O):Jun Liu, Jeffrey T. Borenstein, Piotr Grodzinski, Luke P. Lee, Zhong Lin Wang. DOI: 10.1557/PROC-820-O7.2.
Goryll, M., Wilk, S. J., Laws, G. M., Goodnick S. M., Thornton T. J., Saraniti, M., Tang, J. M. and Eisenberg, R. S. (2003) “Silicon-based ion channel sensor.“ Superlattices & Microstructures 34 (3-6), 451-457. DOI: 10.1016/j.spmi.2004.03.041.
van der Straaten, T. A., Tang, J. M., Ravaioli, U., Eisenberg, R. S. and Aluru, N. R. (2003) “Simulating Ion Permeation Through the OmpF Porin Ion Channel Using Three-Dimensional Drift-Diffusion Theory.“ Journal of Computational Electronics 2(1):29-47. DOI: 10.1023/A:1026212825047.
van der Straaten, T. A., Tang, J. M., Eisenberg, R. S., Ravaioli, U. and Aluru, N. R. (2002) “Three-dimensional Continuum Simulations of Ion Transport Through Biological Ion Channels: Effect of Charge Distribution in the Constriction Region of Porin.“ Journal of Computational Electronics 1(3):335-340. DOI: 10.1023/A:1020787222235.
Tang, J. M., Quandt, F. N. and Eisenberg, R. S. (1995) “Perfusion of patch pipettes.“ In Neuromethods, Patch Clamp Applications and Protocols. Chapter 5. Volume 26:123-139. A.A. Boulton, G.B. Baker and W. Walz, editors. Humana Press, New Jersey. DOI: 10.1385/0-89603-311-2:123.
Tang, J. M., Wang, J. and Eisenberg, R. S. (1992) “Perfusing patch pipettes.“ In Methods in Enzymology. Chapter 10. Volume 207:176-181. B. Rudy and L.E. Iverson, editors. Academic Press, Florida. PMID: 1528117.
Tang, J. M., Wang, J. and Eisenberg, R. S. (1992) “Studies on intact sarcoplasmic reticulum: patch clamp recording and tension measurement in lobster split muscle fibers.“ In Methods in Enzymology. Chapter 48. Volume 207:692-699. B. Rudy and L.E. Iverson, editors. Academic Press, Florida. PMID: 1382208.
Wang, J., Tang, J. M. and Eisenberg, R. S. (1992) “A calcium conducting channel a kin to a calcium pump.“ Journal of Membrane Biology. 130:163-181. PMID: 1283985.
Tang, J. M., Wang, J., Quandt F. N. and Eisenberg, R. S. (1990) “Perfusing pipettes.“ Pflügers Arch. 416:347-350. PMID: 2381768.
Tang, J. M., Wang, J. and Eisenberg, R. S. (1989) “K+-selective channel from sarcoplasmic reticulum of split lobster muscle fibers.“ Journal of General Physiology. 94:261-278. PMID: 2794967. PMCID: PMC2228942.
Cooper, K. E., Tang, J. M., Rae, J. L. and Eisenberg, R. S. (1986) “A cation channel in frog lens epithelia responsive to pressure and calcium.“ Journal of Membrane Biology. 93:259‑269. PMID: 2434653.
Nelson, D. J., Jacobs, E. R., Tang, J. M., Zeller, J. M. and Bone, R. C. (1985) “Immunoglobulin G‑induced single ionic channels in human alveolar macrophage membranes.“ Journal of Clinical Investigation. 76:500‑507. PMID: 2411759. PMCID: PMC423851.
Nelson, D. J., Tang, J. M. and Palmer, L. G. (1984) “Single‑channel recording of apical membrane chloride conductance in A6 epithelial cells.“ Journal of Membrane Biology. 80:81‑89. PMID: 6090667.