Comparative Research Center

The Comparative Research Center oversees all use of animals at Rush for research, testing or teaching, including monitoring studies for compliance with protocols and regulatory requirements.


The animal research facilities consist of a central facility and one smaller satellite facility, occupying approximately 23,000 net square feet. The animal care facilities are run in accordance with the National Institutes of Health Guide for the Care and Use of Laboratory Animals.

Veterinary staff

The center’s staff provide a range of consulting and training services for investigators, including the following:

  • Review of animal use protocols
  • Training in the use of animals in research
  • Assistance with the conduct of research studies

Veterinary staff is responsible for monitoring animal care and use practices and for providing advice and assistance to investigators to complete their research aims and to correct any deficiencies with respect to conformance with applicable policies, laws and regulations.

The veterinary staff provide medical care to all animals housed in the center’s facilities. Research-related animal illnesses are the responsibility of the investigator, who, in consultation with the veterinary staff, should provide necessary treatment and support. Any issue or disagreement between the center’s staff and animal users may be referred to the Institutional Animal Care and Use Committee (IACUC) or the research integrity officer¬†for review and recommendation.

The center’s veterinarians and the IACUC have authorized jurisdiction over all animal use at Rush. They are responsible for following all recommendations in the Guide for the Care and Use of Laboratory Animals to the extent possible within the center’s facilities. Following the guide, veterinarians recommend policies and procedures that will ensure adequate care of all animals at Rush. Along with the advice of the IACUC, veterinarians are authorized to enforce these policies and procedures. The IACUC and veterinarians have the authority to suspend animal use activities. The veterinarians also have final authority in determining when euthanasia is required.


Periodic assessment of the center’s effectiveness is provided at multiple levels by many sources including the following:

  • Semiannual program review and inspection of the facility by the IACUC
  • Annual performance reviews of personnel
  • Annual unannounced inspections by a U.S. Department of Agriculture (USDA) veterinary medical officer
  • Triennial site visits by the American Association for Accreditation of Laboratory Animal Care (AAALAC) International Council on Accreditation
  • Annual reporting to the Office of Laboratory Animal Welfare, USDA and AAALAC

Contact us

Comparative Research Center
Cohn Research Building
1735 W. Harrison St., Suite 206
Chicago, IL 60612
Phone: (312) 942-6576
Fax: (312) 563-3377