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Susan Chubinskaya, PhD

Susan Chubinskaya, PhD
Vice Provost for Faculty Affairs
Department of Pediatrics, RUSH Medical College
The Klaus Kuettner Professor of Osteoarthritis Research Professor, Departments of Pediatrics, Orthopaedic Surgery & Medicine (Section of Rheumatology)
President, Orthopaedic Research Society
Education

Postdoctoral Fellow, Department of Biochemistry, Rush Medical College

PhD, RE Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, National Academy of Sciences of Ukraine 

 

Research Areas

Cartilage repair and regeneration, post-traumatic osteoarthritis, biologic approaches to cartilage repair

 

 

Contact Info:

600 S. Paulina St.
Suite 1044B
Chicago, IL 60612
Phone: (312) 942-6306
susanna_chubinskaya@rush.edu
Links:
Honors and Activities

 

  • American Society of Association Executives/ the Center for Association Leadership training/CEO training
  • The Hedwig van Ameringen Executive Leadership in Academic Medicine® (ELAM) Program at Drexel University College of Medicine
  • Office of Faculty Affairs/Mentoring Programs at Rush University Medical Center has being awarded with the 2019 Group on Women in Medicine and Science (GWIMS/AAMC) Leadership Award for an organization, 2019
  • Orthopaedic Research Society Women Leadership Award, 2017
  • Fellow of International Orthopaedic Research, 2016 (FIOR)
  • Honorary fellow, International Cartilage Repair Society, 2015
  • Jacquelin Perry Resident Research Award for the project by Bhatia S, Bell, R, Frank R, Rodeo S, Bach BR, Cole BJ, Chubinskaya S, Wang VM, Verma NN, Bony Incorporation of Soft Tissue ACL Grafts in an Animal Model: Autograft vs Allograft With Low Dose Gamma Irradiation. AAOS meeting, San Francisco, 2012
  • Who’s Who in America, 2009-14
  • The Ciba-Geigy Professor of Biochemistry, Rush University Medical Center, Chicago (Endowed Chair), 2007
  • Co-recipient of Eugene T. Nordby M.D. Research Award, International Intradiscal Therapy Society, for the outstanding research (best presented paper) presented by M. Kawakami, T. Matsumoto, S. Chubinskaya, H. Hashizume, M. Yoshida. Osteogenic protein-1 (OP-1) injection to degenerative intervertebral discs attenuates pain-related behavior secondary to down-regulation of interleukin-1β and tumor necrosis factor-α. 18th Annual IITS Meeting, San Diego, California, 2005
  • Best Poster Presentation Award, American College of Rheumatology, Frank BS, Kumar B, Merrihew CA, Fisher B, Rueger DC, Block JA, Chubinskaya S, Osteogenic Protein-1 in synovial fluid is a potential marker in arthritis, ACR Annual Meeting, San Francisco, 2003 (Arthritis & Rheum 2001, 44(9):S310)
  • Co-recipient of William J. Stickel Gold Award for publication by Muehleman C, Chubinskaya, S, Cole, A.A., Noskina, Y., Arsenis, C., Kuettner, K.E, Morphological and Biochemical Properties of Metatarsophalangeal Joint Cartilage, 1997 (J Amer Pod Med Assoc, 87 (10), 447-459)
  • Graduate student fellowship, Orthopaedic Institute, Department of Biochemistry, Latvia, 1986
  • Summa cum laude diploma, Department of Chemistry, Kiev State University, Ukraine, 1985
Publications

https://www.ncbi.nlm.nih.gov/pubmed/?term=chubinskaya

Grants
  • NIH RO1 1R01 AR066635-01A1, Maher PI, Subcontract to Rush, Mechanobiological risk factors for initiation of post traumatic osteoarthritis, Role: PI, 04/01/2015-03/31/2020
  • NIH RO1 Loeser PI, Subcontract to Rush, Oxidative stress and the development of osteoarthritis, Role: PI, 09/30/2012-09/30/2017
  • NIH/R13 1R13AR057640-0109 NIH/NIAMS, 2009, 37th Midwest Connective Tissue Workshop, Role: PI
  • NIH/RO1 NIH/NIAD 1R01 AI 055060-01, Protein targets of ovarian and oocyte autoantibodies, J. Luborsky PI, Role: Consultant, 3/1/03-2/28/08
  • NIH/NIAMS SCOR grant P50 AR 39239, Osteoarthritis: a continuum (SCOR), K. Kuettner: Program Director, 01/01/03-12/31/08
    • Project one: Mechanisms involved in the formation of a cartilage tissue by osteoarthritic cells, $127,512, E. Thonar PI, Role: Collaborator 
    • Core B: Biological research core, $132,538, C. Knudson PI, Role: Co-investigator
  • NIH/NIAMS RO1 grant, Hyaluronan-Cell interactions in cartilage, C. Knudson PI, Role: Co-investigator, 04/01/02-03/31/07
  • NIH/NIAMS RO1 grant, Mineral Matrix Relations in Calcifying Tissues, W. Landis PI, Role: Collaborator 04/01/02-03/31/07
  • NIH/RO1 5R01AR047654 NIH/NIAMS grant, Age-related differences in cartilage OP-1, Role: PI
  • NIH/NIAMS SCOR grant P50 AR 39239, Osteoarthritis: a continuum (SCOR), Klaus Kuettner PI, Core B: Biochemistry and Molecular Biology (BMB) Core (T. Glant PI), Role: Collaborator, 04/01/98-03/31/03
  • NIH/NIA R03 AG15548-01 grant, Age-related differences in chondrocyte MMP-8, Role: PI (20%), $50,000. 07/01/98-06/30/99

Industry grants

  • Novartis Institute for Functional Genomics “Understanding mechanisms and pathways involved in disc maintenance and degeneration” Role: PI. 07/011/2019-06/30/2020
  • Jointechlabs “Effect of adipose-derived stromal cells (ASC) on metabolism of human cartilage” Role PI. 0701/2019-06/30/2020. 
  • Joint Restoration Foundation “Prospective, Randomized, Single Blind Clinical Trial to Investigate the Impact of Autologous Bone Marrow Concentrate in Knee Osteochondral Allograft Transplantation” Clinical Trial;  Adam Yanke PI; Role: Co-I. 2018-2019
  • Baxalta US, Inc. “Angiogenesis markers of human hemophilic synovitis” Nakobyan, PI; Chubinskaya, Co-I. 2018-2020;
  • NuTech, The use of amniotic membrane for cartilage repair, Role: PI, 07/01/15-06/30/16
    • NuTech, The use of hypothermically preserved human amniotic membrane in the repair of chondral defects, Role: Co-PI, 06/01/15-01/01/17
  • Ceramtec, In vitro wear testing of living cartilage against alumina, M.Wimmer PI, Role: Co-PI, 03/01/14-12/31/14
  • Mesoblast, Inc., Acquisition and isolation of human intervertebral disc nucleus pulposus and annulus fibrosis cells, Role: PI, 02/01/14-01/31/15
  • CartiHeal, Inc., The mechanism of Agili-C by-phasic implant effect on cartilage healing, Role: PI, 01/01/13-12/31/14
  • MerrimackPharma, Studies of post-traumatic osteoarthritis: continuum, Role: PI, 01/01/13-12/31/14
  • Smith & Nephew grant, Verma PI; Role: Co-investigator
  • Arthrex, Inc., Surgeon reliability in preparation of chondral defect for ACI: evaluation of the calcified cartilage layer”. B. Cole PI, Role: Co-investigator
  • Musculoskeletal Transplant Foundation, Biologic repair of focal chondral defects of the glenoid: autologous matrix induced chondrogenesis with the use of a collagen I/III matrix in a rabbit shoulder model, V. Wang PI, Role: co-investigator, 01/01/-11-12/31/11
  • Zimmer, Inc., Biochemical Analysis of DeNovo formed cartilaginous tissue, Role: PI
  • Zimmer, Inc., Biochemical analysis of cartilage wear, M. Wimmer, PI, Role: Co-PI
  • NFL Charity Foundation. “Damage and repair in cartilage acute trauma model”. Role: PI, 01/01/10-6/30/11
  • Tornier, Inc., M. Wimmer PI, Role: Co-investigator (3%), 2008-09
  • Invibio, Inc., M. Wimmer PI, Role: Co-investigator (5%), 2008-09
  • Alternative Research Grant Program, Response of damaged human cartilage to articular motion – a study utilizing an acute trauma model on human ankles, M. Wimmer PI, Role: Co-investigator;, 2008-09
  • Joint Restoration Foundation, Effect of catabolic mediators and biomechanical load on osteochondral allograft cartilage, Role: PI, 2009-10
  • Regentis, Inc., Biochemical, histological, and structural analysis of newly formed cartilage in the model of osteochondral defects in goats, Role: PI, 2008-10
  • Anesiva, Inc., Rabbit GH Chondrolysis/Rotator Cuff Healing, B. Cole PI, Role: Co-investigator, 07/01/07-06/30/09
  • Stryker Biotech, In vivo and In vitro studies on the role of OP-1/BMP-7 and other members of the BMP family in connective tissue homeostasis, Role: PI, 1999-2008
  • GlaxoWellcome, The role of BMP family and its receptors in the maintaining of articular cartilage, Role: PI, 1998-2001
  • GlaxoWellcome, ADAMs in human cartilage, Role: PI, 1998-2001
  • Procter & Gamble Pharmaceuticals, Inc., Localization of ADAM-10 protein in human normal, damaged and OA cartilages, Role: PI, 1997-98