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Siva Kanangat, PhD D (ABHI)

Siva Kanangat, PhD
Professor
Department of Pathology, RUSH Medical College
Director, Histocompatibility and Immunogenetics Laboratory
Education

Post-Doctoral, University of Tennessee, Knoxville, TN
PhD, Tuberculosis Research Center, University of Madras, India
MS, Christian Medical College, Vellore, University of Madras, India
BS, Malabar Christian College, Calicut, University of Calicut, India

Research Areas

Transplantation immunology: alloimmune responses, autoimmune responses; allograft chronic rejections, biomarkers associated with chronic rejection, epithelial mesenchymal transition in the genesis of chronic rejection manifested by irreversible fibrosis; microbiome and alloimmune responses.

Contact Info:

1109 Jelke
1750 West Harrison St.
Chicago, IL 60612
Phone: (312) 942-2054
Email: sivadasan_kanangat@rush.edu
Links:
Honors and Activities

University Merit Scholarship: 1975-1978. University of Calicut, India.
University Merit Scholarship: 1978-1979. University of Cochin, India.

Publications

https://www.ncbi.nlm.nih.gov/sites/myncbi/collections/bibliography/52822…

Grants

Principal Investigator (R03 NIH): NIAMS, National Institutes of Health: IL-1 and IL-1ra Stimulation of S. aureus Replication (October 1st, 2001- September 30th, 2004) Direct Cost: $150,000/-

Co-Investigator Project # 2: 1-P50AR44890-01A2 Dr. Postlethwaite PI (SCOR)- NIAMS, National Institutes of Health): On the Pathogenesis of Scleroderma; Various aspects of Collagen I and III Biology in SSc and defects of MMP regulation in SSc lesional fibroblasts (August 24th 2001-July 31st July 2006 Total Direct cost of  entire project: $4,380, 000/-

Principal Investigator {Center of Excellence (Connective Tissue Diseases) UT Health Science Center, Memphis} –September 1st 2002- August 31st 2003: Pilot and Feasibility grant: Transdifferentiation of Epithelial cells: Use of RNA silencing strategy to determine the role of key mediators: $ 20,000/Year

Principal Investigator (Rheumatic Diseases Core Center/NIAMS-UT Health Science Center, Memphis): September 1st 2003- August 31st 2006: Mechanisms of TGF-b Mediated differentiation of Human Fibroblasts (An In vitro Model for to study the origin of abnormal fibroblast in patients suffering from systemic sclerosis/Scleroderma). $20,000/year

Principal Investigator: Veteran Affairs, Memphis: Intramural award (Research Enhancement Award Program): October 1st 2005- Mechanisms of fibroblast-Myofibroblat transition: Role of cell density and icIL-1ra. 15,000/year

Co-Principal Investigator of University of Tennessee Medical Group grants (to study the association between inflammatory mediators and bacterial replication extracellularly and intracellular (1997-1998, and 1998-1999, and 1999-2000. $15,000/Year

Invited Presentations

Annual One Lambda-Advanced Workshop on Clinical Histocompatibility. 2014, 2016, 2017
Georgetown University-Dept. Microbiology and Immunology: June 19, 2007.
Hoffman Medical research Laboratory, University of Southern California, Los Angeles, CA
Oct 12, 2007: “Epithelial-Mesenchymal ransition: Role in the genesis of fibrosis”
New York State University, Buffalo, NY: Inflammation- Infections and Fibrosis. October 2002
Food and Drug Administration, Bethesda, MD: March 2001: Inflammation: The good, the bad and the Ugly
National Eye Institute, Bethesda MD: March 1998: Title: Inflammation: A double edged sword
Pfizer Corporation: Jan 1997: Immunopathogenesis of Herpetic stromal keratitis