Meghan Moran, PhD

I am a bone biologist interested in the molecular interactions between the gut, gut microbiome and bone as a mechanistic pathway to delaying or mitigating arthroplasty failure due to peri-implant particle-induced osteolysis.  Osteolysis is inflammatory bone loss, in this case, stimulated by wear particles from the implant. The gut may provide a point of intervention in the inflammatory response to an orthopedic implant and the gut microbiome may act as a biomarker for implant health. My research may lead to a reduced need for invasive revision surgery, which is currently the treatment for failed implants.  Previously, I focused on bone regeneration genetics to identify poor bone repair post-injury.

Boosting Your Microbiome to Strengthen Your Joints

Meghan Moran, PhD Makes Halo Cures 40 Under 40 Chicago Scientists List