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Lai Wang, MD, PhD

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Lai Wang, MD, PhD

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Assistant Professor, Department of Internal Medicine, Division of Rheumatology

RUSH Medical College

Assistant Professor, Department of Internal Medicine, Division of Rheumatology

Contact Information

Address: 1735 W. Harrison St., Suite 522
Phone:
(312) 563-4188
Email:
lai_wang@rush.edu

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MD, Tongji Medical University, Wuhan, China
PhD, Ghent University, Ghent, Belgium
1. Wang L, Shao YY, Ballock RT. Leptin antagonizes peroxisome proliferator-activated receptor-gamma signaling in growth plate chondrocytes. PPAR Research. 2012;2012:756198. PMCID: PMC3458404.

2. Randall RM, Shao YY, Wang L, Ballock RT. Activation of Wnt planar cell polarity (PCP) signaling promotes growth plate column formation in vitro. J Orthop Res. 2012 Dec;30(12):1906-14.

3. Dy P, Wang W, Bhattaram P, Wang Q, Wang L, Ballock RT, Lefebvre V. Sox9 directs hypertrophic

maturation and blocks osteoblast differentiation of growth plate chondrocytes. Dev Cell. 2012 Mar

13;22(3):597-609. PMCID: PMC3306603.

4. Shao YY, Wang L, Welter JF, Ballock RT. Primary cilia modulate Ihh signal transduction in response to

hydrostatic loading of growth plate chondrocytes. Bone. 2012 Jan;50(1):79-84. PMCID: PMC3246537.

5. Wang L, Shao YY, Ballock RT. Leptin synergizes with thyroid hormone signaling in promoting growth plate

chondrocyte proliferation and terminal differentiation in vitro. Bone. 2011 May 1;48(5):1022-7.

6. Wang L, Shao YY, Ballock RT. Thyroid hormone-mediated growth and differentiation of growth plate

chondrocytes involves IGF-1 modulation of beta-catenin signaling. J Bone Miner Res. 2010

May;25(5):1138-46. PMCID: PMC3123724.

7. Wang L, Shao YY, Ballock RT. Carboxypeptidase Z (CPZ) links thyroid hormone and Wnt signaling

pathways in growth plate chondrocytes. J Bone Miner Res. 2009 Feb;24(2):265-73. PMCID: PMC3276606.

8. Wang L, Shao YY, Ballock RT. Thyroid hormone interacts with the Wnt/beta-catenin signaling pathway in

the terminal differentiation of growth plate chondrocytes. J Bone Miner Res. 2007 Dec;22(12):1988-95.

9. Wang L, Shao YY, Ballock RT. Peroxisome Proliferator-Activated Receptor-gamma promotes adipogenic

changes in growth plate chondrocytes in vitro. PPAR Res. 2006;2006:67297. PMCID: PMC1779577.

10. Shao YY, Wang L, Ballock RT. Thyroid hormone and the growth plate. Rev Endocr Metab Disord. 2006

Dec;7(4):265-71.

11. Shao YY, Wang L, Hicks DG, Ballock RT. Analysis of gene expression in mineralized skeletal tissues by

laser capture microdissection and RT-PCR. Lab Invest. 2006 Oct;86(10):1089-95.

12. Wang L, Shao YY, Ballock RT. Peroxisome proliferator activated receptor-gamma (PPARgamma)

represses thyroid hormone signaling in growth plate chondrocytes. Bone. 2005 Sep;37(3):305-12.

13. Shao YY, Wang L, Hicks DG, Tarr S, Ballock RT. Expression and activation of peroxisome

proliferator-activated receptors in growth plate chondrocytes. J Orthop Res. 2005 Sep;23(5):1139-45.

14. Verbruggen G, Wang J, Wang L, Elewaut D, Veys EM. Analysis of chondrocyte functional markers and

pericellular matrix components by flow cytometry. Methods Mol Med. 2004;100:183-208.

15. Wang L, Wang J, Almqvist KF, Veys EM, Verbruggen G. Influence of polysulphated polysaccharides and

hydrocortisone on the extracellular matrix metabolism of human articular chondrocytes in vitro. Clin Exp

Rheumatol. 2002 Sep-Oct;20(5):669-76.

16. Wang L, Almqvist KF, Veys EM, Verbruggen G. Control of extracellular matrix homeostasis of normal

cartilage by a TGFbeta autocrine pathway. Validation of flow cytometry as a tool to study chondrocyte

metabolism in vitro. Osteoarthritis Cartilage. 2002 Mar;10(3):188-98.

17. Wang L, Almqvist KF, Broddelez C, Veys EM, Verbruggen G. Evaluation of chondrocyte cell-associated

matrix metabolism by flow cytometry. Osteoarthritis Cartilage. 2001 Jul;9(5):454-62.

18. Almqvist KF, Wang L, Wang J, Baeten D, Cornelissen M, Verdonk R, Veys EM, Verbruggen G. Culture of

chondrocytes in alginate surrounded by fibrin gel: characteristics of the cells over a period of eight weeks.

Ann Rheum Dis. 2001 Aug;60(8):781-90.

19. Almqvist KF, Wang L, Broddelez C, Veys EM, Verbruggen G. Biological freezing of human articular

chondrocytes. Osteoarthritis Cartilage. 2001 May;9(4):341-50.

20. Wang L, Verbruggen G, Almqvist KF, Elewaut D, Broddelez C, Veys EM. Flow cytometric analysis of the

human articular chondrocyte phenotype in vitro. Osteoarthritis Cartilage. 2001 Jan;9(1):73-84.

21. Almqvist KF, Wang L, Broddelez C, Verdonk R, Veys EM, Verbruggen G. The influence of hydrocortisone

on aggrecan metabolism in human articular chondrocyte cultures: comparison of two different matrices.

Clin Exp Rheumatol. 2000 Nov-Dec;18(6):665-73.

22. Verbruggen G, Cornelissen M, Almqvist KF, Wang L, Elewaut D, Broddelez C, de Ridder L, Veys EM.

Influence of aging on the synthesis and morphology of the aggrecans synthesized by differentiated human

articular chondrocytes. Osteoarthritis Cartilage. 2000 May;8(3):170-9.

Please see [PubMed].

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