Guozhi Xiao, MD, PhD

Guozhi Xiao, MD, PhD, is an internationally renowned bone biologist. Xiao has made several important contributions to the understanding of the molecular control of skeletal development. His work is reported in more than 90 peer-reviewed publications, many in high-profile journals, such as the Journal of Clinical Investigation and Nature Communications. His work has been cited more than 6,300 times with an H index of 36. Xiao is a member of the editorial boards of the Journal of Bone and Mineral Research and the Journal of Biological Chemistry. Xiao’s research focuses on the following areas: determining how osteoblast, osteoclast and chondrocyte formation is controlled under physiological and pathological conditions, defining novel mechanisms that control bone angiogenesis, studying bone-muscle interactions, and studying the role of kindlin-2 signaling in bone and cartilage. By working on these projects, the Xiao laboratory has also maintained a focus on medical issues involving bone and cartilage osteoporosis, osteoarthritis, metastatic osteolytic lesions and fracture healing. Information obtained from these studies will enhance understanding of these pathological processes.