Assistant Professor
Department of Orthopedic Surgery,
RUSH Medical College
Education
PhD, Chinese Academy of Science
Research Areas
Xin's research focuses on the key signal pathways and their genetic regulatory networks in skeletal development and diseases using genetically engineered mice. His team is investigating the genetic interaction between the Wnt/Axins and BMP signaling during skeletal development and homeostasis. Mutations in components of the both Wnt and BMP signaling pathways cause a variety of birth defects, degenerative disorders and bone diseases. The lab is also studying manipulation of the two signaling pathways by specific pharmacological inhibitors during skeletal development and homeostasis.