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Lothar A. Blatter, MD, Dr. med.

The John H. and Margaret V. Krehbiel Professor of Cardiology
Professor, Department of Physiology & Biophysics, RUSH Medical College
Education

MD, University of Bern, Switzerland
Dr Med, University of Bern, Switzerland

Research Areas

Calcium regulation and signaling in the heart and the cardiovascular system, characterization of ion transporters and channels, electrophysiology, excitation-contraction coupling, mitochondrial calcium signaling and energetics, excitation-transcription coupling, and changes in calcium signaling in arrhythmia, hypertrophy and heart failure

Contact Info:

1750 W. Harrison St.
Suite 1422
Chicago, IL 60612
Phone: (312) 563-3238
Fax: (312) 942-8711
lothar_blatter@rush.edu
Links:
Biography

Lothar A. Blatter, MD, Dr. med., is the John H. and Margaret V. Krehbiel Professor of Cardiology and a professor of Physiology and Biophysics at Rush. He received his MD degree and the degree of Doctor of Medicine from the University of Bern in Switzerland. He completed postdoctoral training in physiology and pharmacology at the University of Bern, Switzerland, the Mayo Clinic in Rochester, Minn., and the University of Maryland. He held faculty positions at the University of Maryland in Baltimore, Loyola University Chicago and now at Rush University. He was recognized as an Established Investigator of the American Heart Association and as a Fellow of The Physiological Society. He has authored over 150 research articles and book chapters. Since 1993 he has maintained an active, independent and extramurally funded (NIH, AHA and Leducq Foundation) research program and is actively engaged in graduate and medical teaching. His research focuses on mechanisms of excitation-contraction coupling and cellular calcium signaling in healthy and diseased hearts, using high-resolution imaging techniques, electrophysiological methods and molecular biology approaches.

Honors and Activities
  • John H. and Margaret V. Krehbiel Endowed Professorship of Cardiology
  • Fellow of the Physiological Society
  • Established Investigator of the American Heart Association, 1995-2000
  • Career Development Award, Schweppe Foundation, 1994-97 
  • Myron L. Weisfeldt, MD, Fellow of the American Heart Association - Maryland Affiliate, 1990-91
Publications

Complete list of published work on PubMed

Complete list of published work on Scopus

Grants

Current:

  • NIH R01HL155762 (multiple PIs: Blatter, Banach), IP3 receptor, NOX2 and calcium signaling domains in atrial physiology and pathophysiology
  • NIH R01HL164453 (multiple PIs: Blatter, Banach), Atrial excitation-contraction coupling, calcium signaling and electro-mechanical alternans
  • American Heart Association, post-doctoral fellowship; Recipient: Maria Yuriana Oropeza-Almazan (Sponsor: Lothar A. Blatter), Mitochondrial calcium signaling, ROS production and atrial alternans

Completed:

  • NIH R01HL134781 (PI: Blatter), Pathophysiological regulation of atrial myocyte excitation-contraction coupling and calcium signaling
  • NIH R01HL132871 (multiple PIs: Blatter, Banach), Pathophysiological regulation of atrial alternans and atrial fibrillation
  • NIH R01HL057832 (multiple PIs: Fill, Blatter, Chen), Limiting pathological calcium induced calcium release in heart
  • NIH P01HL080101 (Blatter, Project leader), Ca and InsP3 receptor signaling in cardiac myocytes
  • NIH R01HL101235 (Blatter, multiple principal investigators), Mitochondrial dysfunction in cardiac hypertrophy and failure
  • NIH R01HL062231 (PI: Blatter), E-C coupling and Ca2+ regulation in atrial myocytes
  • Leducq Foundation Transatlantic Network (Blatter, Associate Member), Redox and nitrosative regulation of cardiac remodeling: novel therapeutic approaches for heart failure