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| Last Name: | Kanangat |
| First Name: | Sivadasan |
| M. I.: | |
| Degree & Certifications: | PhD |
| Endowed Professorship: | |
| Rank & Title: | Assistant Professor and
Director, Histocompatibility & Immunogenetics |
| Department: | Pathology |
| College: | GME, Rush Medical College |
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| Office Location: | 1750 W. Harrison
Jelke Building
Suite 1109
Chicago, IL 60612
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| Laboratory Location: | 1750 W. Harrison
Jelke Building
Suite 1188
Chicago, IL 60612
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| Phone: | (312) 942-2054 |
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| E-mail: | sivadasan_kanangat@rush.edu |
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| Education: | Christian Medical College, Vellore & Tuberculosis Research Center, University of MADARS, INDIA
1990-MSc, PhD
St. Jude Childrens's Research Hospital: Histocompatibility &Immunogenetics: Director Training-2010
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| Research Areas: | Immune System Diseases |
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Textbooks
Book chapters
Rouse BT and Sivadasan Kanangat. Chapter 8: Herpes simplex virus: In Persistent viral Infections. Ahmed R and Chen I {Eds}: John Wiley and Sons Ltd, UK, p: 165. 1999
Selected Bibliography
- Zhou B, Kermany MH, Glickstein J, Cai Q, Cai C, Zhou Y, Nair U, Kim JW, Kim P,Liu W, Kanangat S, Yoo TJ. Murine autoimmune hearing loss mediated by CD4(+) Tcells specific for ?-tubulin. Clin Immunol. 2011 Feb;138(2):222-30. Epub 2010 Dec9. PubMed PMID: 21145286.
- Kanangat S, Postlethwaite A, Cholera S, Williams L, Schaberg D. Modulation of virulence gene expression in Staphylococcus aureus by interleukin-1beta: novel implications in bacterial pathogenesis. Microbes Infect. 2007 Mar;9(3):408-15.Epub 2007 Jan 12. PubMed PMID: 17307379.
- Kanangat S, Postlethwaite AE, Higgins GC, Hasty KA. Novel functions of intracellular IL-1ra in human dermal fibroblasts: implications in the pathogenesis of fibrosis. J Invest Dermatol. 2006 Apr;126(4):756-65. PubMed PMID:16456536.
- Postlethwaite AE, Shigemitsu H, Kanangat S. Cellular origins of fibroblasts: possible implications for organ fibrosis in systemic sclerosis. Curr Opin Rheumatol. 2004 Nov;16(6):733-8. Review. PubMed PMID: 15577612.
- Meduri GU, Kanangat S. Glucocorticoid treatment of sepsis and acute respiratory distress syndrome: time for a critical reappraisal. Crit Care Med. 1998 Apr;26(4):630-3. PubMed PMID: 9559593.
- Kanangat S, Bronze MS, Meduri GU, Postlethwaite A, Stentz F, Tolley E, Schaberg D. Enhanced extracellular growth of Staphylococcus aureus in the presence of selected linear peptide fragments of human interleukin (IL)-1beta and IL-1 receptor antagonist. J Infect Dis. 2001 Jan 1;183(1):65-69. Epub 2000 Nov 10. PubMed PMID: 11076706.
- Kanangat S, Babu JS, Knipe DM, Rouse BT. HSV-1-mediated modulation of cytokine gene expression in a permissive cell line: selective upregulation of IL-6 gene expression. Virology. 1996 May 1;219(1):295-300. PubMed PMID: 8623544.
- Kanangat S, Thomas J, Gangappa S, Babu JS, Rouse BT. Herpes simplex virus type 1-mediated up-regulation of IL-12 (p40) mRNA expression. Implications in immunopathogenesis and protection. J Immunol. 1996 Feb 1;156(3):1110-6. PubMed PMID: 8557986.
- Kanangat S, Blair P, Reddy R, Daheshia M, Godfrey V, Rouse BT, Wilkinson E. Disease in the scurfy (sf) mouse is associated with overexpression of cytokine genes. Eur J Immunol. 1996 Jan;26(1):161-5. Erratum in: Eur J Immunol. 2003 Jul;33(7):2064. Deheshia M [corrected to Daheshia M]. PubMed PMID: 8566060.
- Kanangat S, Nair S, Babu JS, Rouse BT. Expression of cytokine mRNA in murine splenic dendritic cells and better induction of T cell-derived cytokines by dendritic cells than by macrophages during in vitro costimulation assay using specific antigens. J Leukoc Biol. 1995 Feb;57(2):310-6. PubMed PMID: 7531747.
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