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Assistant Professor of Medicine
Department of Internal Medicine, Section of Rheumatology
Internal Medicine
GME, Rush Medical College
1611 W Harrison St
Suite 510
Chicago, IL 60612

(312) 563-2800
(312) 563-2075
Michigan State University College of Human Medicine

Research Interest
Major Academic Community Activities
   Invited Lectures
Document Links/Web Links or Videos

Sonali Khandelwal, MD, is an assistant professor in the Department of Internal Medicine at Rush Medical College. Khandelwal is board-certified in internal medicine and rheumatology and serves as an attending physician at Rush University Medical Center in Chicago, Illinois and the John H. Stroger, Jr. Hospital of Cook County. She is director of the Rush Connective Tissue Disease Clinic and co-director of the Rush Osteoporosis Treatment Center.

Khandelwal is a member of the American College of Rheumatology, the Chicago Rheumatism Society, the National Osteoporosis Foundation and the Osteogenesis Imperfecta Foundation. Her clinical interests include rheumatoid arthritis and osteoporosis with a special interest in the inherited collagen diseases—specifically, osteogenesis imperfecta, Marfan's syndrome and Ehlers-Danlos. Khandelwal has also obtained training and developing clinical use of the musculoskeletal ultrasound for the diagnosis and treatment of rheumatologic conditions.

Khandelwal was an invited author of a chapter for a premier rheumatology textbook. She has presented abstracts at the national American College of Rheumatology meeting, Orthopedic Research Society meeting and the International Congress on SLE.

Khandelwal received her medical degree from Michigan State University College of Human Medicine. She completed her residency in internal medicine at Rush University Medical Center, where she served as a chief resident, followed by a fellowship in rheumatology at Rush.

Research Interest

Khandelwal is primarily a clinician, however practicing in an enriched medical community has found an unmet need in the area for the care of adults with inherited collagen disorders (osteogensis imperfecta, Ehlers-Danlos and Marfan's syndrome). Many of the individuals with these conditions have been living with them since childhood, but as they transition to adulthood there is a lack of medical guidance. Much of this is due to insufficient observational and longitudinal data for the inherited connective tissue diseases.

The goal of the Connective Tissue Disease Clinic is to establish a center for these individuals to receive specialized medical care. Though in its early phases, this clinic is growing. Thanks to a partnership with Shriner’s Hospital in Chicago we have been able to provide for several individuals with osteogenesis imperfecta.

Ultimately, the goal of Khandelwal’s research is to report longitudinal observational data on the routine management, novel treatment modalities and health outcomes for each population of individuals so that the overall care for these individuals can be enhanced.

Major Academic Community Activities

Invited Lectures

Rush Oak Park Internal Medicine Grand Rounds
January 2012
“Osteoporosis: Update on Diagnosis and Treatment”
Sponsor: Rush Medical Center
Rush Geriatrics Grand Rounds
January 2012
“Osteoporosis: Update on Diagnosis and Treatment”
Sponsor: Rush Medical Center
Rush University Internal Medicine Grand Rounds
November 2010
Case presentation and Discussant. “Hip and Back pain”
Sponsor: Rush Medical Center


  1. Block JA, Khandelwal S. Regional Disorders of the Neck, Shoulder, Arm, and Hand. In: Weisman M, Weinblatt M, Louie J, and van Vollenhoven L, editors, Targeted Treatment of the Rheumatic Diseases, 1st Edition, Saunders-Elsevier, pp. 331-356, 2010.
  2. Jolly M, Khandelwal S, Mikolaitis RA, Weisman MH, Wallace DJ, Block JA. Ethnic Variations in Auto Antibodies Prevalence in Lupus. Lupus, 2010, 19(1s): 123.
  3. Khandelwal S, Jolly M, Block JA. Dyslipidemia in patients with Systemic Lupus erythematosus. Lupus, 2010, 19(1s): 145.
  4. Jolly M, Khandelwal S, Block JA. Positive Health Behaviors and Health Outcomes in Systemic Lupus Erythematosus. Lupus, 2010, 19(1s): 145.
  5. Shakoor N, Foucher KC, Wimmer MA, Mikolaitis RA, Khandelwal S, Block JA. Gait alterations and their association with radiographic severity and pain in unilateral hip osteoarthritis. Osteoarthritis Cartilage, 18(Suppl 2):S67-S68, 2010.
  6. Khandelwal S, Shakoor N, Teodori M, Fogg L, Block JA. The tuning fork as a method of measuring vibratory perception in osteoarthritis of the knee. Transactions of the Orthopaedic Research Society, 35:1032228, 2010.
  7. Jolly M, Pickard AS, Mikolaitis R, Wilke C, Khandelwal S, Rodby R, Block JA. Disease Activity, Body Image and Health Status in Lupus. Arthritis Rheum, 54(Suppl):1113, 2007.
  8. Jolly M, Pickard AS, Wilke C, Khandelwal S, Rodby R, Fogg L, Block JA. Satisfaction with Care and Health Status in Lupus. Arthritis Rheum, 54(Suppl):171, 2007.
  9. Jolly M, Pickard AS, Wilke C, Lin HW, Khandelwal S, Rodby R, Block JA. Development and Validation of a US Lupus Specific Patient Reported Outcome Measure. Arthritis Rheum, 54(Suppl):170, 2007.
  10. Wilke CT, Jolly M, Block JA, Khandelwal S, Rodby R, Pickard AS. Ability of SF-36 and EQ-5D to discriminate among disease activity levels in lupus. Value in Health, 2007, 10(3): A15.
  11. Wilke CT, Jolly M, Khandelwal S, Rodby R, Block JA, Pickard AS. Understanding limitations of patient reported clinical outcomes in lupus. Value in Health, 2007, 10(3): A92.


Student Continuity Experience Rush Medical College, Family Practice Clerkship  
Kaori Yoshida, M2
James Saunders, M2
Rush College of Nursing, NP Program  
Nina Farenbach

Document Links/Web links or videos

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Sonali Khandelwal, MD
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