|Last Name: ||Predescu|
|First Name: ||Dan|
|M. I.: ||N. |
|Degree & Certifications: ||MD|
|Endowed Professorship: |
|Rank & Title: ||Assistant Professor |
|College: ||Graduate College, Rush Medical College|
|Office Location: ||1750 W. Harrison St.|
Chicago, IL 60612
|Laboratory Location: ||1750 W. Harrison St.|
Chicago, IL 60612
|Phone: ||(312) 563-2436|
|Fax: ||(312) 563-3552|
|Education: ||MD, School of Medicine Carol Davila, Bucharest, Romania, 1973|
Internship in laboratory medicine, School of Medicine, Bucharest, Romania
|Research Areas: ||Biological Phenomena Cell Phenomena and Immunity, Biological Sciences, Cardiovascular Diseases, Circulatory and Respiratory Physiology, Genetic Structures, Informatics, Physiological Processes, Viruses|
|Laboratory Techniques: ||Animal surgery/Modeling, Antibody Production, Bioinformatics, Chromatography, Cytokine Assessment, ELISA Development, Gene Chip Technologies, Gene Transfection, Imaging Techonology, Immunohisto-/immunocytochemistry, Microscopy (Electron Transmission Fluorescence Confocal), PCR, Proteomics, Real-time PCR, Spectrophotometry, Transgenic Animal Technology/Microinjection, Ultra centrifugation techniques, Western Northern Southern Blotting|
|Faculty/Staff Description: ||
Vesicular carriers and trafficking, pulmonary fibrosis, receptors and effectors.
The laboratory has a solid record of using electron microscopy as the main imaging method. The emphasis is on TEM and SEM with a particular attention for immunostaining, quantitation and spatial reconstruction. We are also using many methods from light microscopy including immunostaining on fixed and semi thin cryo sections, FRET, FRAP and confocal microscopy.
Area of Research
The preferred area of research is vascular biology with emphasis on endothelial heterogeneity, cellular signaling, signaling to and from cytoskeleton, inter-endothelial communications, and endothelial interaction with themselves and with their surroundings. My special interest is on the development and adequate usage of molecular methods particularly the one related to gene expression and gene activity control.