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Al-Harthi
Lena
PhD
Professor and Associate Chair
Immunology-Microbiology
Graduate College, Rush Medical College
1735 W. Harrison St.
Cohn Research Building
Room 614
Chicago, IL 60612

1735 W. Harrison St.
Cohn Research Building
Room 644
Chicago, IL 60612

(312) 563-3220
(312) 942-2808
lalharth@rush.edu
1996, PhD, Immunology and Microbiology, George Washington University, Washington, DC

1991, MS, Biology, American University, Washington, DC

1989, BS, Biology, American University, Washington, DC, graduated Magna Cum Laude
Nervous System Diseases, Virus Diseases, Viruses
Animal surgery/Modeling, Cytokine Assessment, Flow Cytometry, Gene Chip Technologies, Gene Transfection, Laser Capture, PCR, Real-time PCR, si RNA, Spectrophotometry, Ultra centrifugation techniques, Western Northern Southern Blotting

Lena Al-Harthi, PhD, is a professor and the associate chair of the Department of Immunology/Microbiology at Rush University Medical Center in Chicago, Ill. Al-Harthi received her PhD from the George Washington University in microbiology. Her dissertation research was conducted as an NIH pre-intramural research training fellow at the laboratory of tumor cell biology, headed by Dr. Robert Gallo, a co-discoverer of HIV and under the mentorship of Dr. Suresh Arya. She then conducted her post-doctoral training in HIV immunology at Rush University Medical Center in the laboratory of Alan Landay, PhD. Her research over the past 16 years has focused on HIV/host interactions, with a special emphasis on bridging basic and clinical science in the HIV/AIDS field. Because of her experience in HIV molecular biology, immunology and NeuroAIDS, she has been able to probe mechanistic questions that are clinically relevant to HIV/AIDS. Her group has identified the β-catenin signaling pathway as an important regulator of HIV replication in multiple compartments, including the central nervous system. Through multiple NIH-funded studies, she is investigating the molecular pathway by which β-catenin regulates HIV replication, its impacts on HIV neuropathogenesis, and the role of host and viral factors in modulating β-catenin interaction with HIV. Al-Harthi has over 60 peer-reviewed publications and reviews and has given many invited talks worldwide relating to HIV pathogenesis, especially in the central nervous system. She served on national and international grant review study sections, where she chaired or co-chaired several of these panels, and is currently the chair of the NeuroAIDS and other End-Organ Diseases (NAED) NIH study section. She serves on the editorial boards of several journals, was the program director for the Division of Immunology/Microbiology at Rush for eight years, and she continues to be actively engaged in mentoring graduate students, post-doctoral fellows and junior faculty.
 
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