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Landay
Alan
L.
PhD
The Thomas J. Coogan, Sr., MD, Professor
Professor
Chairman
Facilitator
Immunology-Microbiology
GME, Graduate College, Rush Medical College
1725 W. Harrison St.
Professional Office Building
Ste. 306
Chicago, IL 60612-3823

1735 W. Harrison St.
Cohn Research Building
Ste. 641
Chicago, IL 60612-3823

(312) 942-2849
(312) 942-2808
alanday@rush.edu
PhD, University of Pittsburgh, 1981

BS, Pennsylvania State University, 1976

Biological Phenomena Cell Phenomena and Immunity, Immune System Diseases, Virus Diseases
Cytokine Assessment, Flow Cytometry

Selected Publications:
1. Hunt PW, Shulman N, Hayes TL, Dahl V, Somsouk M, Funderburg NT, McLaughlin B, Landay AL, Adeyemi O, Gilman LE, Clagett B, Rodriguez B, Martin JN, Schacker TW, Shacklett BL, Palmer S, Lederman MM, Deeks SG. The immunologic effects of maraviroc intensification in treated HIV-infected individuals with incomplete CD4+ T cell recovery: a randomized trial. Blood. 2013 April 15. PMID: 23589670.

2. Makinde HM, Zariffard R, Mirmonsef P, Novak RM, Jarret O, Landay AL, Spear GT. IL-22 levels are associated with Trichomonas vaginalis infection in the lower genital tract. Amer J Reprod Immunol. 2013 February 27. PMID: 23445169.
 
3. Parrinello CM, Landay AL, Hodis HN, Gange SJ, Norris PH, Young M, Anastos K, Tien PC, Xue X, Lazar J, Benning L, Tracy RP, Kaplan RC. Treatment-related changes in serum lipids and inflammation: clinical relevance remains unclear. Analyses from the Women’s Interagency HIV Study. AIDS. 2013 February 21. PMID: 23435295.
 
4. Siewe B, Stapleton JT, Martinson J, Keshavarzian A, Kazmi N, Demarais PM, French AL, Landay A. Regulatory B cell frequency correlates with markers of HIV disease progression and attenuates anti-HIV CD8+ T cell function in vitro. Jour Leukocyte Biology. 2013 February 22. PMID: 23434518.
 
5. Martin GE, Gouillou M, Hearps AC, Angelovich TA, Cheng AC, Lynch F, Cheng WJ, Paukovics G, Palmer CS, Novak RM, Jaworowski A, Landay AL, Crowe SM. Age-associated changes in monocyte and innate immune activation markers occur more rapidly in HIV infected women. Plos One 8(1):e55279, 2013. PMID: 23365694. PMCID: PMC3554695.
 
6. Mirmonsef P, Zariffard M, Gilbert D, Hadijat M, Landay A, Spear G. Short chain fatty acids induce pro-inflammatory cytokine production alone and in combination with toll-like receptor ligands. Amer Jour Reprod Immun. Amer J Reprod Immunology 67(5):391-400, 2012. PMID: 22059850. PMCID: PMC3288536.
 
7. Tassiopoulos K, Landay, A, Collier A, Connick E, Deeks S, Hunt P, Lewis D, Wilson C, Bosch R. CD28-negative CD4+ and CD8+ T-cells in ART-naïve HIV-infected adults enrolled in ACTG studies. J. Infect Dis 205(11):1730-8, 2012. PMID: 22448010. PMCID: PMC3415854.
 
8. Kaplan RC, Landay AL, Hodis HN, Gange S, Norris PJ, Young M, Anastos K, Tien PC, Xue N, Lazar J, Parrinello C, Benning L, Tracy R. Potential cardiovascular disease risk markers among HIV-infected women initiating antiretroviral treatment. J Acquir Immune Defic Syndr 60(4):359-68, 2012. PMID: 22592585. PMCID: PMC3400505.
 
9. Parrinello CM, Sinclair E, Landay AL, Lurain N, Sharrett AR, gange SJ, Xue X, Hunt P, Deeks SG, Hodis HN, Kaplan RC. Cytomegalovirus IgG antibody is associated with subclinical carotid artery disease among HIV-infected women. J. Infect. Dis 205(12):1788-96, 2012. PMID: 22492856. PMCID: PMC3415890.
 
10. Pandrea I, Cornell E, Wilson C, Ribeiro R, Ma D, Kristoff J, Xu CL, Haret-Richter G, Trichel A, Apetrei C, Landay A, Tracy R. Coagulation biomarkers predict disease progression in SIV-infected nonhuman primates. Blood 2012 120(7):1357-66, 2012. PMID: 22653975. PMCID: PMC3423778.
 
11. Villacres MC, Kono N, Mack WJ, Nowicki MJ, Anastos K, Augenbraun M, Liu C, Landay A, Greenblatt R, Gange S, Levine AL. IL10 responses are associated with sustained CD4 T cell counts in treated HIV infection. J Infect Dis 206(5): 780-9, 2012. PMID: 22693231. PMCID: PMC3491747.
 
12. Anthony DD, Conry SJ, Medvik K, Rani S, Falck-Ytter S, Blanton RE, Lederman MM, Rodriguez B, Landay AL, Sandberg JK. Baseline sCD14 and CD16+56- NK frequency are negatively associated with response to IFN/RBV therapy during HCV-HIV infection. Jour Infect Dis 2012 Jul 10. [Epub ahead of print]. PMID: 22782948. PMCID: PMC3501153.
 
13. Wilkin TJ, Lalama C, McKinnon J, Gandhi R, Lin N, Landay A, Ribaudo H, Fox L, Currier J, Mellors JW, Gulick R, Tenorio AR. A pilot trial of adding maraviroc to suppressive antiretroviral therapy for suboptimal CD4+ T-cell recovery despite sustained virologic suppression: ACTG A5256. J Infect Dis 206:534-42, 2012. PMID: 22740718. PMCID: PMC3491731.
 
14. Hearps AC, Martin GE, Angelovich TA, Cheng W-J, Maisa A, Landay AL, Jaworowski A, Crowe SM. Aging is associated with chronic innate immune activation and dysregulation of monocyte phenotype and function. Aging Cell. 2012 Jun 18. Doi: 10.1111/j.1474-9726.2012.00851 x. [Epub ahead of print]. PMID: 22708967.
 
15. Stapleton JT, Chaloner K, Martinson JA, Zhang J, Klinzman D, Xiang J, Desai S, Landay A. GB virus C infection is associated with altered lymphocyte subset distribution and reduced T cell activation and proliferation in HIV-infected individuals. PLoS One 7(11):e50563, 2012. PMID: 23209780. PMCID: PMC3510065.
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