Biomechanics: Faculty Research Interests
Dr. Alejandro Espinoza
develops methods to analyze joint/spine motion and loading patterns in both normal populations as well as in those altered by degenerative conditions such as arthritis/disc degeneration or aging. His research focuses on analysis of structure-function relationships in bone and joints.
Dr. Nadim James Hallab
is director of the Biomaterials Laboratory and is interested in the biocompatibility of orthopedic implants. He investigates: 1) implant debris, both ions, particles and metal-protein complexes, 2) implant degradation from corrosion and wear of modular junctions, 3) immune reactivity to implant debris, 4) cell toxicity responses to implant debris, 5) potentiodynamic surface optimization for directing cell bioreactivity, and 6) novel implant fixation and surgical techniques using in vitro mechanical testing.
Dr. Nozomu Inoue
works on spine biomechanics, specifically the biomechanics of spinal surgery and the effect of degenerative changes of discs and facet joints on segmental instability and motion. Currently his major research areas are development of 3D medical image-based computer models for quantitative analyses of spinal alignment and facet kinematics.
Dr. Joshua J. Jacob’s
interest is in analyzing biocompatibility of permanent orthopedic implants; corrosion and wear of metallic biomaterials; clinical performance of joint replacement devices.
Dr. Hannah Lundberg
combines novel computational and experimental modalities to better represent joint (natural and implant) function in vivo and improve surgical outcomes. Current emphasis is on using computer modeling to predict total knee replacement forces and behavior during everyday life.
Dr. Raghu Natarajan’s
interest is in the development of Finite Element models of hip and knee joints as well as models of both lumbar and cervical spines. His current modeling activity includes development of models of lumbar spine with varying degree of degenerative disease and understand how adjacent disc disease progresses in patients.
Dr. Vincent Wang
uses biomechanical, imaging and extracellular matrix biologic approaches in animal models to study mechanisms of tendinopathy. Particular emphasis is placed on the roles of ADAMTS enzymes in aberrant matrix remodeling as well as the potential therapeutic benefit of mechanical loading in promoting tendon healing.
Dr. Markus Wimmer
investigates the effects of load and motion in human joints. Using both gait analysis and in vitro simulation, he studies wear and lubrication of natural and artificial joints. He is working on a better understanding of the degradation mechanisms in vivo, and trying to enhance preclinical wear testing methods.
Dr. Mathew Mathew’s interest is in corrosion and tribocorrosion of biomaterials. Tribocorrosion is a combined study of wear and corrosion and their synergistic interactions in relation to orthopedic implants, particularly hip prostheses. The study has significant implications on the patients with implants, which are exposed to mechanical articulation and under adverse chemical in-vivo environment (infections, varying pH levels etc). He is also a Research Assistant Professor at College of Dentistry, UIC. Chicago. He leading the tribocorrosion research in dentistry (Dental Implants and Temporomadibular Joints (TMJ)) and actively involved in the Institute of Biomaterials, Tribocorrosion and Nano-medicine (IBTN).
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