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The Graduate College > Neuroscience > Neuroscience Research Activities
About Rush University

The background and expertise of the faculty cover a broad range of fields within the neurosciences, including:

  • Behavioral and cognitive neuroscience
  • Neurophysiology
  • Neuroanatomy
  • Neuropsychopharmacology
  • Cell and molecular biology
  • Circadian rhythms and sleep

Research among the faculty is especially strong in the following areas:

  • Transplantation and regeneration
  • Neurobiological bases of normal memory and of its dysfunction
  • Aging
  • Neurobiological bases of degenerative disorders, such as Alzheimer's disease and Parkinson's disease
  • Huntington's disease
  • Stroke
  • Pathophysiology of epilepsy

Faculty members also have expertise and conduct ongoing research in quantitative structural and functional imaging. Thus, depending on interest, numerous interdisciplinary research areas are available to the student.

Neurobiology of Mild Cognitive Impairment in the Elderly
Program project funded by the National Institute on Aging (PO1 AG14449)

Dr. Elliott Mufson, Rush University Medical Center
Program Director

Advancement of our understanding of the relationship between the brain and memory problems in the elderly, as well as the design of effective treatments and therapies for brain diseases and disorders is a task requiring the scientific expertise and dedication of many researchers. Rush University Medical Center is the home of a major NIA funded research program project grant entitled Neurobiology of mild cognitive impairment in the elderly directed by Dr. Elliott Mufson, Alla and Solomon Jesmer Chair in Aging, Professor of Neurological Sciences. This program project brings together the expertise of scientists in the areas of aging and dementia at Rush, with distinguished researchers located at other major academic research centers including:

Dr. Lester Binder, Northwestern University Medical School, Chicago

Dr. Steven DeKosky, University of Virginia School of Medicine

Dr. Stephen Ginsberg, Nathan Kline Institute, NYU Medical Center

Dr. Milos Ikonomovic, University of Pittsburgh

Dr. James Lah, Emory University, Atlanta

Dr. Allan Levey, Emory University, Atlanta

Dr. Stephen W. Scheff, University of Kentucky

Dr. Sue Leurgans, Rush University Medical Center


Past Members of the Program Project:

Dr. Dennis Dickson, Mayo Clinic, Jacksonville
Drs. John Trojanowski and Virginia T. Lee, University of Pennsylvania Medical School

The research program has an Administrative and Tissue Distribution Core (Director, Elliott Mufson) and a Statistical and Date Management Core (Director, Dr. Sue Leurgans). The program project works closely with the Rush Alzheimer’s Disease Center

Program Project selected publications from 165 peer reviewed articles

Mufson, E.J., Jaffar, S. and Levey, A.I.: m2 muscarinic acetylcholine receptor immunoreactive neurons are not reduced within the nucleus basalis in Alzheimer’s disease: Relationship with cholinergic and galaninergic perikarya. J. Comp. Neurol., 392: 313-329, 1998.

Cochran, E.J., J.A. Schneider, Bennett, D.A., Mufson, E. J.: Application of the NIA/Reagan Institute working criteria for the diagnosis of Alzheimer's disease to members of the Religious Orders Study. J. Neuropath. Exp. Neurol , 57:508, 1998.

Mufson, E. J., Chen, E-Y., Cochran, E. J., Beckett, L. A., Bennett, D. A. and Kordower, J. H.: Entorhinal cortex beta amyloid load in individuals with mild cognitive impairment. Exp. Neurol., 158, 469-490, 1999.

Gilmor, M.L., Erickson, J. D., Varoqui, H., Hersh, L.B., Bennett, D. A., Cochran, E. J., Mufson, E. J., and Levey, A. I.: Preservation of nucleus basalis neurons containing choline acetyltransferase and the vesicular acetylcholine transporter in the elderly with mild cognitive impairment and early Alzheimer's disease. J. Comp Neurol. 411:693-704, 1999.

Mufson, E. J., Ma, S. Y., Cochran, E. J., Bennett, D. A., Beckett, L. A., Jaffar, S., Saragovi , H. U. and Kordower, J. H.: Loss of nucleus basalis neurons containing trkA immunoreactivity in individuals with mild cognitive impairment and early Alzheimer’s disease. J. Comp. Neurol., 427: 9-30, 2000.

Kordower, J H., Chu, Y., Stebbins, G. T., DeKosky, S. T., Cochran, E.J., Bennett, D. and Mufson, E. J.: Loss and atrophy of layer II entorhinal cortex neurons in elderly people with mild cognitive impairment. Ann. Neurol., 49, 202-213, 2001.

Ghoshal, N., Garcia-Sierra, F., Fu, Y., Beckett, L.A., Mufson, E.J., Kuret, J., Berry, R.W., and Binder, L.I. Tau-66: Evidence for a novel tau conformation in Alzheimer's disease. J. Neurochem., 77: 1372-1385, 2001.

Chu, Y., Cochran, E. J., Beckett, L. A., Bennett, D. A. Mufson, E. J. and Kordower, J. H.: Down-regulation of trkA mRNA within nucleus basalis neurons in individuals with mild cognitive impairment and Alzheimer’s disease. J. Comp. Neurol., 437: 296-307, 2001.

Gomez-Ramos, P., Mufson, E.J. and M.A. Moran: Apolipoprotein E immunoreactivity in neurons and extracellular neurofibrillary tangles in aged non-demented and Alzheimer’s disease brain. J. Microscopy Res. Tech., 55: 48-58, 2001.

Bennett DA, Wilson RS, Schneider JA, Evans DA, Beckett LA, Aggarwal NT, Barnes LL, Fox JH, Bach J. Natural history of mild cognitive impairment in older persons. Neurology. 2002 Jul 23;59(2):198-205.

Mitchell, T. W., Mufson, E. J., Schneider, J. A., Cochran, E. J., Nissanov, H., J., L-Y,

Bienias, J. L., Lee, V. M.-Y., Trojanowski, J. Q., Bennett, D. A. and Arnold, S. E.: Parahippocampal tau pathology in healthy aging, mild cognitive impairment and early Alzheimer's disease, Ann. Neurol., 51: 182-189, 2002.

Mufson, E. J. Counts, S. E. and Ginsberg, S. D.: Gene expression profiles of cholinergic nucleus basalis neurons in Alzheimer’s disease, Neurochem. Res., 27, 1033-1046, 2002.

DeKosky ST, Marek K. Looking backward to move forward: early detection of neurodegenerative disorders. Science. 2003 Oct 31;302(5646):830-4.

Lad, S. P., Neet, K. E. and Mufson, E J.: Nerve growth factor: structure, function and therapeutic implications for Alzheimer’s disease. Curr. Drug Target CNS Neurol. Disord. 2: 315-34, 2003.

Kus, L., Borys, E., Chu, Y-P, Ferguson, S. M., Blakely, R. D., A.I., Emborg, M., Kordower, J.H., Levey A. I. and Mufson, E. J.: Distribution of high affinity choline transporter immunoreactivity in the primate central nervous system. J. Comp. Neurol. 463:341-357, 2003

Wang D-S, Bennett, D.A., E. J. Mufson, E. J., Cochran, E., and Dickson, D. W.: Contribution of changes in ubiquitin and myelin basic protein to age-related cognitive decline, J. Neurosci. Res., 48: 93-100,2004.

Ginsberg, S. D., Elarova, I., Ruben, M., Tan, F., Counts, S. E., Eberwine, J.H., Trojanowski, J. Q., Hemby, S. E., Mufson, E. J. and Shaoli, C.: Single cell gene expression analysis: implications for neurodegenerative and neuropsychiatric disorders. Neurochem. Res. 29: 1053-1064, 2004.

Peng, S, Wuu, J., Mufson, E. J. and M. Fahnestock: Increased proNGF levels in subjects with mild cognitive impairment and mild Alzheimer’s disease, J. Neuropath. Exper. Neurol., 63: 641-549, 2004.

Mufson, E. J.: Reduction of cortical TrkA but not p75NTR protein in early stage Alzheimer’s Disease, Ann. Neurol., 56:520-531. 2004.

Bennett DA, Schneider JA, Bienias JL, Evans DA, Wilson RS. Mild cognitive impairment is related to Alzheimer disease pathology and cerebral infarctions. Neurology. 2005 Mar 8;64(5):834-41.

Counts, S.E. and Mufson, E. J.: The role of nerve growth factor receptors in cholinergic basal forebrain degeneration in prodromal Alzheimer’s disease, J. Neuropath. Exper. Neurol., 64: 263-272, 2005.

Peng, S., Wuu, J., Mufson, E. J. and Fahnestock, M.: ProBDNF and mature BDNFare decreased in the preclinical stages of Alzheimer’s disease, J. Neurochem., 93:1412-1421, 2005.

Tuszynski, M.T., Thal, L., Pay, M., Salmon, D. P., U. Hoi Sang, Bakay, R., Patel, P., Blesch, A., Vahlsing, H. L., Ho, G., Tong, G., Potkin, S. G., Fallon, J., Masliah, E., Mufson, E. J., Kordower, J. H., Gall, C. and Conner, J.: A phase I clinical trial of nerve growth factor gene therapy for Alzheimer’s disease, Nat. Med., 11, 551-555, 2005.

Wang, D.S., Bennett D.A., Mufson E.J. and Dickson, D.W.: Isopeptide correlates with neuropsychological status better than tissue transglutaminase protein or enzyme activity level. J. Neuropathol. Exp. Neurol., 64: 440, 2005.

Ginsberg, S.D., Che, S., Wuu, J., Counts, S. E. and Mufson, E. J.: Down regulation of trk but not p75NTR gene expression in single cholinergic basal forebrain neurons mark the progression of Alzheimer’s disease. J. Neurochem., 97:475-487, 2006.

Forman, M.S. Mufson, E.J., Leurgans, S., Pratico, D., Joyce, S., Leight, S., Lee, V.M.-Y. and Trojanowski, J.Q.: Cortical Biochemistry in MCI and Alzheimer Disease, Neurology, 68: 757-763, 2007.

Albrecht, S., Bourdeau, M. Bennett, D., Mufson, E. J., Bhattacharjee and LeBlanc, A.: Activation of caspase-6 in aging and mild cognitive impairment, Am. J. Path. 170, 1200-2009, 2007.

Scheff, S. W., Price, D. A., Schmitt, F. A. DeKosky, S. T. and Mufson, E. J.: Synaptic alterations in CA1 in mild Alzheimer's disease and mild cognitive impairment. Neurology, 68: 1501-1508. 2007.

Ikonomovic, M. D., Abrahamson, E. E., Isanski, B. A., Wuu, J., Mufson, E. J. and DeKosky, S.T.: Superior frontal cortex cholinergic axon density in mild cognitive impairment and early Alzheimer’s disease, Arch. Neurol., 64: 1312-1317, 2007.

Mufson, E. J, Counts, S. E., Fahnestock, M. and Ginsberg, S. D.: Cholinotrophic molecular substrates of mild cognitive impairment in the elderly, Current Alzheimer’s Res., 4: 340-350, 2007.

Counts, S.E., He, B, Che, S., Ikonomovic, M. D., DeKosky, S. T., Ginsberg, S. D. and Mufson, E. J.: α7 nicotinic receptor up-regulation in cholinergic basal forebrain neurons in early stage Alzheimer’s disease, Arch. Neurol., 64: 1771-1776, 2007.

Sager, K.L., Wuu, J., Leurgans, S.E., Rees, H.D., Gearing, M., Mufson, E. J., Levey, A.I. and Lah, J.J.: Neuronal LR11/SorLA expression is reduced in mild cognitive impairment, Ann. Neurol., 62: 640- 647, 2007.

Counts, S., He, B, Che, S., Ginsberg, S. D. and Mufson, E. J.: Galanin hyperinnervation up-regulates choline acetyltransferase expression in cholinergic basal forebrain neurons in Alzheimer’s disease, Neurodegen. Dis., 5: 228-231, 2008.

Wang, D-S: Uchikado, H., Bennett, D., Schneider, J. A., Mufson, E. J., Wuu, J. and Dickson, D.W.: Cognitive performance correlates with cortical isopeptide immunoreactivity as well as Alzheimer’s pathology, JAD, 13: 53-66, 2008.

Mufson, E. J., Counts, S. E., Perez, S. E., and Ginsberg, S. D.: Cholinergic system during the progression of Alzheimer's disease: therapeutic implications. Expert Rev Neurother.8, 1703-1718, 2008. PMCID: 2631573 doi: 10.1586/14737175.8.11.1703.

Ikonomovic, M.D., Wecker, L., Abrahamson, E.E., Wuu, J, Counts, S.E., Ginsberg, S.D., Mufson, E.J. and DeKosky, S.T.: Cortical α7 nicotinic receptor and -amyloid levels in early Alzheimer’s disease, Arch Neurol., 66:646-651, 2009.

Peng, S., Garzon, D. J., Marchese, M., Klein, W., Ginsberg, S. D., Francis, B., Mount, H.T.J, Mufson, E. J, Salehi, A. and Fahnestock, M.: Decreased brain-derived neurotrophic factor depends upon amyloid aggregation state in transgenic mouse models of Alzheimer's disease. J. Neurosci., 29:9321-9329, 2009.

Bruno, M. A., Mufson, E.J., Wuu, J., Cuello, A. C.: Increased MMP-9 activity in mild cognitive impairment, J. Neuropath. Exp. Neurol, 68, 1309-1318,2009.

Mufson, E.J. and Leurgans, S.: Inability of plasma and urine F2A isoprostane levels to differentiate mild cognitive impairment from Alzheimer’s disease, Neurodegen. Dis., 7:139-142, 2010.

Mufson, E. J., Wuu, J., Counts, S. Nykjaer, E. A.: Preservation of cortical sortilin protein levels in MCI and Alzheimer’s disease, Neurosci. Lett., 471, 129-133, 2010.

Counts, S.E. and E.J. Mufson: Putative CSF protein biomarker candidates for amnestic mild cognitive impairment, Translational Neuroscience, 1, 2-8, 2010.

Ginsberg, S. D., Alldred, M. J., Counts, S. E., Cataldo, A. M., Neve, R. L., Jiang, Y., Wuu, J., Chao, M. V., Mufson, E. J., Nixon, R. A. and Che, S.: Microarray analysis of hippocampal CA1 neurons implicates early endosomal dysfunction during Alzheimer's disease progression, Biological Psychiatry, 15:68:885-93, 2010.

Ginsberg, S.D., Mufson, E.J., Counts, S.E., Wuu, J., Alldred, M.J., Nixon, R.A., and Che, S.: Regional selectivity of rab5 and rab7 protein up regulation in mild cognitive impairment and Alzheimer’s disease. J. Alz. Dis., 22, 631-639, 2010.

Scheff, S. W., Price, D. A., Schmitt, F. A., Scheff, M. A. and Mufson, E. J.: Synaptic loss in the inferior temporal gyrus in mild cognitive impairment and Alzheimer disease, J. Alz. Dis., 24, 547-557, 2011.

Ikonomovic, M. D., Klunk, W. E., Abrahamson, E., E., Wuu. J., Mathis, C. A., Scheff, S. W., Mufson, E. J. and DeKosky, S. T.: Precuneus amyloid burden is associated with reduced cholinergic activity in Alzheimer’s disease, Neurology, 77:39-47, 2011.

George, S., Mufson, E. J., Leurgans, S., Shah, R.C., Ferrari, C., deToledo-Morrell, L.: MRI-based volumetric measurement of the substantia innominata in amnestic MCI and mild AD, Neurobio. Aging, 32: 1756-1764, 2011 PMID: 20005600.

Ginsberg, S.D., Mufson, E.J., Alldred, M.J., Counts, S.E., Wuu, J., Nixon, R.A., and Che, S.: Upregulation of select rab GTPases in cholinergic basal forebrain neurons in mild cognitive impairment and Alzheimer’s disease. J. Chem. Neuroanat., 42: 102-110, 2011.

Counts, S.E., Che, S., Ginsberg, S. D., and Mufson, E.J: Gender differences in NGF receptor expression in cholinergic nucleus basalis neurons during the progression of Alzheimer's disease J. Chem. Neuroanat., 42: 111-117, 2011.

Patterson KR, Remmers C, Fu Y, Brooker S, Kanaan NM, Vana L, Ward S, Reyes JF, Philibert K, Glucksman MJ, Binder LI. Characterization of prefibrillar Tau oligomers in vitro and in Alzheimer disease. J Biol Chem. 2011 Jul 1;286(26):23063-76.

Counts, S. E., He, B., N, Muhammad, Wuu. J. and Mufson, E. J.: Hippocampal drebrin loss in mild cognitive impairment, Neurodegenerative Dis., 10: 216-219, 2012.

Himmelstein DS, Ward SM, Lancia JK, Patterson KR, Binder LI. Tau as a therapeutic target in neurodegenerative disease. Pharmacol Ther. 2012 Oct;136(1):8-22.

Perez, S. E., Getova, D. P., He, B., Counts, S. E., Geula, C., Desire, L., Coutadeur, S., Peillon, H., Ginsberg, S. D., Mufson, E. J.: Rac1b increases with progressive tau pathology within cholinergic nucleus basalis neurons in Alzheimer’s disease, Am. J. Path. 180: 526-540, 2012.

Vana, L., Kanaan, N. M., Ugwu, I. C., Wuu, J., Mufson, E. J. and Binder, L. I.: Progression of tau pathology in cholinergic basal forebrain neurons in MCI and AD, American J. Path, 179: 2533-2550, 2011.

Mufson, E. J., Binder, L., Counts, S. E., DeKosky, S. T., deTolledo-Morrell, Ginsberg, S. D., Milos D. Ikonomovic5, Perez, S. E. and Scheff, S. W.: Mild Cognitive Impairment: Pathology and mechanisms, Acta Neuropathologica, 123: 13-30, 2012 (peer reviewed).

Sager, K. L., Wuu, J., Herskowitz, J, Mufson, E. J., Levey, A. I., Lah, J. J.: Neuronal LR11 expression does not differentiate between clinically-defined Alzheimer’s disease and control brains, PLoS, 7, 2012.

Mufson, E. J., He, B., Nadeem, M., Perez, S. E., Counts, S. E., Leurgans, S., Fritz, J., Lah, J., Ginsberg, S. D., Wuu, J. and S. W. Scheff: Hippocampal proNGF signaling pathways and -amyloid levels in mild cognitive impairment and Alzheimer’s disease, JNEN, 71: 1018-1029, 2012.

Ward SM, Himmelstein DS, Lancia JK, Binder LI. Tau oligomers and tau toxicity in neurodegenerative disease. Biochem Soc Trans. 2012 Aug;40(4):667-71.

Scheff, S. W., Price, D.A, Schmitt, F.A., Roberts, K.N., Ikonomovic, M.D. and Mufson, E. J.: Synapse stability in the precuneus early in the progression of Alzheimer’s disease, JAD, in press.

Book Chapters

Mufson, E. J., Sobreviela, T. and Kordower, J. H.: Chemical neuroanatomy of the primate insula cortex: Relationship to cytoarchitectonics, connectivity, function and neurodegeneration. In: Handbook of Chemical Neuroanatomy: The Primate Nervous System, Part I: vol. 13. (Eds.) Bloom, F., Bjorklund, A. and Hokfelt, T., Elsevier Science, Amsterdam, Netherlands, pp. 377-454, 1997.

Mufson, E. J. and Kordower, J. H.: Nerve growth factor and its receptors in the primate forebrain: Alterations in Alzheimer’s disease and potential use in experimental therapeutics. In: Neuroprotective Signal Transduction. Mattson, M.P. (Ed.), Humana Press, pp. 23-59, 1997.

Mufson, E.J.: NGF, p75NTR and trkA in Alzheimer’s disease: Neural Notes, Promega, vol. III, pp. 16-19, 1997.

Tuszynski, M. H., Gage, F. H., Mufson, E. J. and Kordower, J. H.: Neurotrophic factors, gene therapy and Alzheimer's disease. In: CNS Regeneration: Basic Science and Clinical Advances. M. Tuszynski and J. H. Kordower (Eds.), Academic Press, Mufson, E. J. and Kordower, J. H.: Nerve growth factor in Alzheimer’s disease. In: pp. 505-528, 1998.

Mufson, E. J. and Kordower, J. H: Nerve growth factor in Alzheimer’s disease. In: Cerebral Cortex. A. A. Peters and J.H. Morrison (Eds.) Kluwer Academic/Plenum Press, New York, vol. 14, pp.681-731, 1999.

Mufson, E. J. and Kordower, J. H.: Cholinergic Basal Forebrain Systems in the Primate Central Nervous System: Anatomy, Connectivity, Neurochemistry, Aging, Dementia and Experimental Therapeutics. In: Functional Neurobiology of Aging. (Eds.) P. R. Hof and C. V. Moobs, Academic Press, San Diego, pp. 243-276, 2000.

Mufson, E.J., Gilmor, M, Ma, S.Y., Levey, A. I. and Kordower, J. H.: Phenotypic Differences in Cholinergic Markers within the Nucleus Basalis in Individuals with Mild Cognitive Impairment. In: Advances in Etiology, Pathogenesis and Therapeutics. K. Iqbal, S.S. Sisodia and B. Winblad (Eds.) John Wiley & Sons, Ltd., Chichester, England, 2001.

Wang, D-S. Cochran, E. J., Bennett, D.A., Mufson, E.J. and Dickson, D.W.: Amyloid, PHF-tau, Ubiquitin and Synaptic Markers in the Progression of Alzheimer’s disease: Immunochemical Analyses of Frontal Cortex from Prospectively Studied Elderly Humans. In: Advances in Etiology, Pathogenesis and Therapeutics. K. Iqbal, S.S. Sisodia and B. Winblad (Eds.) John Wiley & Sons, Ltd., Chichester, England, 2001.

Mufson, E. J. and Counts, S. E.: Basocortical Cholinotrophic Dysfunction During the Early Stages of Alzheimer's Disease, In: Alzheimer's Disease and Related Disorders: Clinical and Basic Research Advances, Eds. K. Iqbal, and B. Winblad, Electronic book published by Alzheimer's Association, pp. 202-210, 2004.

Mufson, E.J., Counts, S.E., Peng, S. and Fahnestock, M.: Shift in the Balance of trkA and pro-NGF in Prodromal Alzheimer’s Disease In: Alzheimer’s and Parkinson’s Diseases: Insights, Progress and Perspectives, I. Hanin, M. Memo and F. Stocchi and A. Fischer (Eds.) Medimond, Bologna, Italy, pp. 203-209, 2005.

Fahnestock, M., Peng, S., Garzon, D. and Mufson, E.J.: Is Decreased pro-BDNF the Cause of Alzheimer's-Associated Neurodegeneration and Cognitive decline? In: Alzheimer’s and Parkinson’s Diseases: Insights, Progress and Perspectives, I. Hanin, M. Memo and F. Stocchi and A. Fischer (Eds.) Medimond, Bologna, Italy, pp. 225-230, 2005.

DeKosky, S. T., Ikonomovic, M. D., Hamilton, R. L., Bennett, D. A. and Mufson, E. J.: Neuropathology of Mild Cognitive Impairment in the Elderly, Eds. Gauthier, Boca Raton FL, (Eds.) S. Gauthier, P. Scheltens and J. L. Cummings, 1-17 pp. 1-16, 2005.

Ginsberg, S.D., Hemby, S.E., Mufson, E.J., and L.J, Martin: Cell and tissue microdissection in combination with genomic and proteomic applications. In L. Zaborszky, F. G. Wouterlood, and J.L. Lanciego (Eds); Neuroanatomical Tract Tracing 3: Molecules, Neurons, and Systems, New York, Springer, pp. 109-141, 2006.

Mufson, E.J., Counts, S.E., Fahnestock, M. and Ginsberg, S. D.: NGF Family of Neurotrophins and their Receptors: Early Involvement in the Progression of Alzheimer’s Disease, In: Neurobiology of Alzheimer’s Disease, 3rd Edition, D. Dawbarn and S.J. Allen (Eds.), Oxford University Press, England, 2006.

Mufson, E. J., Counts, S. E., Che, S., and Ginsberg, S. D.: Neuronal Gene Expression Profiling: Uncovering the Molecular Biology of Neurodegenerative Disease. In: Functional Genomics and Proteomics in the Clinical Neurosciences, Eds. S.E. Hemby and Bahn, S.: Prog. Brain Res., Elsevier, Amsterdam, vol. 158C, 197-222, 2006.

Ginsberg, S.D., Che, S., Counts, S.E., and Mufson, E.J.: Gene expression abnormalities mark the progression of Alzheimer's disease. In Sun, M.K. (ed): Research Progress in Alzheimer's Disease and Dementia, Hauppauge: Nova Science Publishing, vol. 3, 25-58, 2008.

Mufson, E J., Counts, S. E. and Ginsberg, S. D.: Neuropharmacology-neurotransmitters-growth factors: Cholinergic Systems, Encyclopedia of Neuroscience, ed. L. Squire, Oxford, Academic Press, vol. 2, 845-856, 2009.

Mufson, E.J., Counts, S. E., Perez, S. E. and Ginsberg, S. D.: Cholinergic Systems in Aging and Alzheimer’s disease: Neurotrophic and Molecular Analysis, In: Koob G.F., Le Moal M. and Thompson R.F. (eds.) Encyclopedia of Behavioral Neuroscience, Oxford: Academic Press, vol. 1, 249-256, 2010.

Scheff, S. W., Ginsberg, S., Counts, S. E. and Mufson, E. J.: Synaptic integrity in mild cognitive impairment and Alzheimer’s disease, In: Research Progress in Alzheimer’s Disease and Dementia (V), ed. Miao-Kun Sun (Blanchette Rockefeller Neurosciences Institute, Rockville, MD), NOVA Scientific Publisher, NY, 2012.

Gandy, S. and DeKosky, S.T.: Toward the treatment and prevention of Alzheimer's disease: rational strategies and recent progress. Annu Rev Med. 2013;64:367-83.

 


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