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WHI official Website
“The Women's Health Initiative (WHI) is a long-term national health study that focuses on strategies for preventing heart disease, breast and colorectal cancer and fracture in postmenopausal women. This 15-year project involves over 161,000 women ages 50-79, and is one of the most definitive, far-reaching programs of research on women’s health ever undertaken in the U.S.” - www.whi.org, March 6, 2007
Principal Site Investigator
William Elliott, M.D.
The WHI Memory Study (WHIMS)
WHI participants who are randomized to the hormone therapy trial and who also agree to be a part of WHIMS undergo annual testing to determine presence of cognitive decline and dementia. The first phase of the trial, funded by Wyeth-Ayerst, determined that hormone therapy in the form of combined estrogen and progesterone was associated with a small but significant increase in dementia and cognitive decline for women who had an intact uterus. NIH funding is pending to determine the long-term impact of hormone therapy on dementia and to determine the effects of unopposed estrogen on cognitive function in women who have had a hysterectomy.
Principal Site Investigator
Lynda H. Powell PhD.
The WHI Study of Cognitive Assessment (WHISCA)
This is an ancillary study conducted in conjunction with the WHI. It involves approximately 14 WHI clinical sites. The study aims to determine the relationship between hormone therapy and the early decline in cognitive function in post-menopausal women.
Principal Site Investigator
Lynda H. Powell PhD.
Project Director
Barbara Mascitti
Barbara_J_Mascitti@rush.edu
(312) 563-2209
Staff
Marcin Wiesyk
Marcin_Wiesyk@rush.edu
Arline Wilson
Arline_M_Wilson@rush.edu
Funding:
NIH
NHLBI
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