Thomas Hoeppner, Ph.D. Associate Professor, Neurological Sciences -Named Outstanding Teacher by graduating class Rush Medical College (Alternative Curriculum) 2002
		Education B.S. - City College of New York 1965 M.A. - McMaster University 1967 Ph. D. - McMaster University 1971 Post-doctoral Fellow in Brain Research - New York Medical College 1970-1972

Contact Information Address: Department of Neurological Sciences 1653 W. Harrison St. Chicago, IL 60612 Business Phone: (312)942-5943 E-mail Address: Thomas_J_Hoeppner@rsh.net Research Interests Mechanisms of epilepsy: Studies of the effects of amygdala kindling on fear conditioning in rodents utilize the kindling model of epilepsy to understand the alteration in emotional behavior in the interictal period frequently observed in some patients with epilepsy. Studies of the distribution of anticonvulsants in the brain examine the neuroanatomic specificity of anticonvulsant drug action. Studies of the neuroprotective action of anticonvulsants are searching for non-toxic agents with multiple actions that both provide protection from seizures and reduce the neuronal loss that may occur as a result of seizures. Human studies of the distribution of epileptic activity and eloquent areas in the brain utilize various source localization procedures to minimize functional impairment.

Representative Publications Hoeppner, T.J. The anticonvulsant valproic acid concentrates in the olfactory bulb: selective laminar localization. Brain Research 532:326-328, 1990. Hoeppner, T.J., Morrell, F., Smith, M.C., Chez, M.G., Hasegawa, H. The Landau-Kleffner Syndrome: A peri-Sylvian epilepsy. Epilepsia 33, Suppl. 3:122, 1992. Hoeppner, T.J., Smith, M.C., deToledo-Morrell, L., Reimschisel, T.E., Wolter, J.A. Amygdala kindling and fear conditioning. Neurosci. Abstr. 22:1117, 1996. Morrell, F., Kanner, A.M., deToledo-Morrell, L., Hoeppner, T., Whisler, W.W. Multiple subpial transection. Adv Neurol;81:259-70, 1999. Hoeppner, T., Smith, M. Models of psychopathology in epilepsy. Lessons learned from animal studies. In Psychiatric Issues in Epilepsy: A practical guide to diagnosis and treatment. A. Ettinger and A. Kanner, eds. Lippincott, Williams and Wilkins, PA, 2001.